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Nature 302, 495-500 (7 April 1983) | doi:10.1038/302495a0; Received 27 August 1982; Accepted 19 January 1983

Frequency of fixation of adaptive mutations is higher in evolving diploid than haploid yeast populations

Charlotte Paquin* & Julian Adams

  1. Division of Biological Sciences, University of Michigan, Ann Arbor, Michigan 48109, USA
  2. *Present address: ARCO Plant Cell Research Institute, 6560 Trinity Court, Dublin, California 94566, USA.
  3. To whom reprint requests should be addressed.
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Adaptive mutations are shown to have a higher frequency of fixation in evolving diploid than in haploid populations of the yeast Saccharomyces cerevisiae, providing direct evidence that it may be an evolutionary advantage to be diploid.