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Article
Nature 290, 221-225 (19 March 1981) | doi:10.1038/290221a0; Accepted 24 December 1980
The E. coli
-lactamase attenuator mediates growth rate-dependent regulation
Bengtåke Jaurin, Thomas Grundström, Thomas Edlund & Staffan Normark
- Department of Microbiology, University of Umeå, S-901 87 Umeå, Sweden
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Abstract
We have identified a new control or attenuator region in the chromosomal 
-lactamase operon of Escherichia coli. A single base alteration within this attenuator led to a loss in the cell's ability to coordinate its content of -lactamase with growth rate. We suggest a mechanism through which this mode of regulation operates.
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