Abstract
The nucleotide sequence spanning the ribosomal RNA (rRNA) genes of cloned human mitochondrial DNA reveals an extremely compact genome organization wherein the putative tRNA genes are probably ‘butt-jointed’ around the two rRNA genes. The sequences of the rRNA genes are significantly homologous in some regions to eukaryotic and prokaryotic sequences, but distinctive ; the tRNA genes also have unusual nucleotide sequences. It seems that human mitochondria did not originate from recognizable relatives of present day organisms.
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Eperon, I., Anderson, S. & Nierlich, D. Distinctive sequence of human mitochondrial ribosomal RNA genes. Nature 286, 460–467 (1980). https://doi.org/10.1038/286460a0
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DOI: https://doi.org/10.1038/286460a0
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