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Intermediate filaments as mechanical integrators of cellular space

Abstract

Five chemically distinct classes of intermediate filaments can be identified within higher eukaryotic cells. Each class is characteristic of a particular cell type. These filaments may function to integrate mechanically the various structures of the cytoplasmic space in a way that is tailored to the differentiated state of the cell

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Lazarides, E. Intermediate filaments as mechanical integrators of cellular space. Nature 283, 249–255 (1980). https://doi.org/10.1038/283249a0

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