Nature 279, 197 - 201 (17 May 1979); doi:10.1038/279197a0

Cell-surface antigens induced by RNA tumour viruses

R. Kurth^*, E. M. Fenyö^†, E. Klein^† & M. Essex^‡

^*Friedrich Miescher Laboratory, Max Planck Institute, Spemannstrasse 37−39, 74 Tübingen, FRG
^†Department of Tumor Biology, Karolinska Institute, Stockholm 60, Sweden
^‡Department of Microbiology, Harvard University, School of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115

Host animals show an immune response to the surface of cells infected with RNA tumour viruses. An element of this response is due to expression of viral structural antigens, but the major part is due to virus-induced cell-surface antigens (CSAs). This article compares the properties of CSAs of the avian, murine and feline retrovirus systems.

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