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Cultivation of malarial parasites

Abstract

The method for continuous cultivation of Plasmodium falciparum has now been successfully applied to several strains from different geographical areas. It has been used for tests of antimalarial drugs, for studies of parasite–host cell interactions with special reference to sickle haemoglobin, and for the production of amounts of parasite material sufficient for experimental immunisation of Aotus trivirgatus monkeys.

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References

  1. Developments in Malaria Immunology, Tech. Rep. Ser. Wld Hlth Org. 579 (1975).

  2. Beaudoin, R. L. Bull. Wld Hlth Org. 55, 373–376 (1977).

    CAS  Google Scholar 

  3. Vanderberg, J. J., Weiss, M. M. & Mack, S. R. Bull. Wld Hlth Org. 55, 377–392 (1977).

    CAS  Google Scholar 

  4. Trager, W. & Jensen, J. B. Science 193, 673–675 (1976).

    Article  ADS  CAS  Google Scholar 

  5. Jensen, J. B. & Trager, W. J. Parasit. 63, 883–886 (1977).

    Article  CAS  Google Scholar 

  6. Trager, W. Conference on Tropical Medicine, London, 1977 (Royal Society of Medicine, London, in the press).

  7. Jensen, J. B. & Trager, W. Am. J. trop. Med. Hyg. (in the press).

  8. Allison, A. C. Ann. N.Y. Acad. Sci. 91, 710–729 (1961).

    Article  ADS  CAS  Google Scholar 

  9. Siddiqui, W. A. Science 197, 388–389 (1977).

    Article  ADS  CAS  Google Scholar 

  10. Carter, R. & Beach, R. F. Nature 270, 240–241 (1977).

    Article  ADS  CAS  Google Scholar 

  11. Trager, W., Robert-Gero, M. & Lederer, E. FEBS Lett. 85, 264–266 (1978).

    Article  CAS  Google Scholar 

  12. Friedman, M. Proc. natn. Acad. Sci. U.S.A. (in the press).

  13. Pasvol, G., Weatherall, D. J. & Wilson, R. J. M. Nature 270, 171–173 (1977).

    Article  ADS  CAS  Google Scholar 

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Trager, W., Jenson, J. Cultivation of malarial parasites. Nature 273, 621–622 (1978). https://doi.org/10.1038/273621a0

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