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Article
Nature 271, 726-730 (23 February 1978) | doi:10.1038/271726a0; Received 24 October 1977; Accepted 6 January 1978
Novel cell cycle control of RNA synthesis in yeast
R. S. S. Fraser* & Paul Nurse
- Department of Zoology, University of Edinburgh, West Mains Road, Edinburgh, UK
- *Present address: Biochemistry Section, National Vegetable Research Station, Wellesbourne, Warwick, UK.
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Abstract
During the fission yeast cell cycle, the rate of polyadenylated messenger RNA synthesis doubles when the cell reaches a critical size. This size-related control maintains average mRNA content in balance with total cell mass during exponential growth, even in cells growing at different absolute growth rates per cell.
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