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Nature 256, 376 - 379 (31 July 1975); doi:10.1038/256376a0

Signal-to-noise ratio of electron micrographs obtained by cross correlation

J. Frank & L. Al-Ali

Cavendish Laboratory, Cambridge, UK

The signal-to-noise ratio of electron micrographs can be determined by two-dimensional digital cross correlation even though neither signal nor noise can be analysed separately. Such measurements suggest how best to make use of the electron microscope.

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