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Nature 248, 588 - 590 (12 April 1974); doi:10.1038/248588a0

Zinc ions inhibit replication of rhinoviruses


Central Research Department, E. I. du Pont de Nemours and Company, Experimental Station, Wilmington, Delaware 19898

THE rhinoviruses comprise a subgroup of the picornaviruses, distinguished by their acid lability. They are medically important as the infectious agents of the common cold in man. Although there have been reports of chemical agents which inhibit rhinovirus replication, in only a few instances has the mode of antiviral action been demonstrated at a biochemical level1,2.



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