Nature 247, 461 - 462 (15 February 1974); doi:10.1038/247461a0

Human Normoblast A Antigen seen by Immunoelectron Microscopy

F. REYES, J. L. LEJONC, M. F. GOURDIN, H. TON THAT & J. BRETON GORIUS

Unité de Recherches sur les Anémies (U.91 INSERM), CHU Henri Mondor 94010—Creteil

MEMBRANE antigens are extensively studied on different mammalian cell lines. Antigens of the erythrocyte series are often chemically well defined heterosaccharide determinants¹, the subject of numerous studies, most of them restricted to the mature circulating erythrocytes. There are only a few reports dealing with the detection of blood group antigens on erythrocyte precursor cells²⁻⁵. Yunis and Yunis² gave strong evidence of the presence of A, B and H alloantigens on human normoblasts, mostly by indirect agglutination methods involving living bone marrow cells.

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