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Article
Nature 243, 150 - 154 (18 May 1973); doi:10.1038/243150a0

Double Helix at Atomic Resolution

JOHN M. ROSENBERG, NADRIAN C. SEEMAN, JUNG JA PARK KIM, F. L. SUDDATH, HUGH B. NICHOLAS* & ALEXANDER RICH

Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
*Present address: Biophysics Laboratory, University of Wisconsin, Madison, Wisconsin 53706.

The sodium salt of the dinucleoside phosphate adenosyl-3′,5′-uridine phosphate crystallizes in the form of a right handed antiparallel double helix with Watson-Crick hydrogen bonding between uracil and adenine. A sodium ion is located in the minor groove of the helix complexed to both uracil rings.

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