Cannabivarin and Tetrahydrocannabivarin, Two New Constituents of Hashish

Abstract

WE have identified two more constituents of hashish to add to the constituents of hashish already known¹. In 1969 Vollner et al.² identified cannabidivarin, a cannabidiol homologue in which the side chain is C₃H₇ instead of C₅H₁₁. All cannabinoids found until then had contained an olivetyl group (n-amylresorcinol). This was the first cannabinoid found which contained a divarinyl group (n-propylresorcinol). Because many constituents are derived from cannabidiol and cannabidiolic acid, Vollner et al. predicted that hashish would yield more constituents derived from cannabidivarin, and indeed Gill et al.³ found in ‘Tincture of Cannabis’ (BPC) a Δ¹-tetrahydrocannabinol homologue with C₃H₇, instead of C₅H₁₁ as the side chain.