Selective Neurone Death as a Possible Memory Mechanism
Department of Zoology, University of Oxford
IT is a widely deplored fact that every day many thousands of our brain cells die and, unlike other types of cell, are never replaced1,2. I suggest that this may not be a purely destructive process, as is normally supposed, but may represent a mechanism for one of the brain's most constructive functions, memory or information storage.
||Brody, H., J. Comp. Neurol., 102, 511 (1955).
||Burns, B. D., The Mammalian Cerebral Cortex (Arnold, London, 1958).
||Darwin, C. R., On the Origin of Species by Means of Natural Selection (1859).
||Pringle, J. W. S., Behaviour, 3, 174 (1951).
||Diamond, M. C., Krech, D., and Rosenzweig, M. R., J. Comp. Neural., 123, 111 (1964).
||Diamond, M. C., Law, F., Rhodes, H., Lindner, B., Rosenzweig, M. R., Krech, D., and Bennett, E. L., J. Comp. Neurol., 128, 117 (1966).
||Andrew, W., J. Comp. Neurol., 70, 413 (1939).
||Andrew, W., and Cardwell, E. C., Arch. Path., 29, 400 (1940).
© 1971 Nature Publishing Group