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Article
Nature 228, 1264 - 1268 (26 December 1970); doi:10.1038/2281264a0

Transfer RNA Methylases and Cancer

VALDA M. CRADDOCK

Biochemical Mechanisms Section, Toxicology Unit, MRC Laboratories, Carshalton, Surrey

There is much evidence to suggest that tRNA methylases in tumours differ from the enzymes in normal tissues. The experimental basis and possible significance of the changes in activity and in specificity of these enzymes are discussed in this article.

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