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Nature 227, 901 - 903 (29 August 1970); doi:10.1038/227901a0

Rejection of Skin Allografts by Radiation Chimaeras: Selective Gene Action in the Specification of Cell Surface Structure

EDWARD A. BOYSE, EUGENE M. LANCE, ELIZABETH A. CARSWELL, SHEILA COOPER & LLOYD J. OLD

Sloan-Kettering Institute for Cancer Research, and The Hospital for Special Surgery, New York, NY 10021

Use of the technique of acquired tolerance suggests that epidermal cells contain distinctive transplantation allo-antigens—antigens not also possessed by marrow and lymphoid cells.

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