Nature 224, 1175 - 1178 (20 December 1969); doi:10.1038/2241175a0

Effect of -Adrenergic Blockade and Alcohol on Simulated Car Driving

V. GOLDMAN, B. COMERFORD, D. HUGHES & G. NYBERG

Department of Anaesthesia, Institute of Dental Surgery, Gray's Inn Road, London WC1
AB Hässle, Gothenburg
London Hospital, London E1
AB Hässle, Gothenburg

A new adrenergic -receptor antagonist, alprenolol, may be of benefit to drivers with ischaemic heart disease. It does not significantly impair performance nor worsen the effects of alcohol.

References

1.	Hoffmann, H., and Reygers, W., Zentralbleit, Verkehrsmed., 3, 131 (1960).
2.	Hoffmann, H., Heft Z. Unfallheilkunde, 71, 127 (1962).
3.	Hoffmann, H., München Med. Wochenschr., 105, 1790 (1963). | ChemPort |
4.	Hoffmann, H., Verkehrssicherheit, 11, 145 (1965).
5.	Simonson, E., Baker, C., Burns, N., Keiper, C., Schmitt, O. H., and Stackhouse, S., Amer. Heart J., 75, 125 (1968). | Article | PubMed | ISI | ChemPort |
6.	Brändström, A., Corrodi, H., Junggren, U., and Jönsson, T.-E., Acta Pharmaceut. Sver., 3, 303 (1966).
7.	Åblad, B., Brogård, M., and Ek, L., Acta Pharmacol., 25, Suppl. 2, 9 (1967).
8.	Dupuis, H., Proc. II Kong. J. Ges. K. Arbeitswissenchaft, Suppl. 3, 78 (1965).
9.	Hughes, D. T. D., Cramer, F., and Knight, G. J., Med. Sci. Law, 7, 200 (1967). | PubMed | ISI | ChemPort |
10.	Taggart, P., and Gibbons, D., Brit. Med. J., i, 411 (1967).
11.	Eliasch, H., Rosén, A., and Scott, H., Circulation, 32, Suppl. 2, 81 (1965). | ISI |
12.	Rosén, A., Kreislauf-Bücher, 23, 83 (1967).
13.	Forsberg, S. Å., and Johnsson, G., Acta Pharmacol., 25, Suppl. 2, 75 (1967). | ChemPort |
14.	Robinson, B. F., Circulation, 35, 1073 (1967). | PubMed | ISI | ChemPort |
15.	Björntorp, P., Acta Med. Scand., 182, 285 (1967). | PubMed |
16.	Björntorp, P., Acta Med. Scand., 184, 259 (1968). | PubMed |
17.	Aubert, A., Nybergm, G., Slaastad, O., and Tjeldflaat, L., Proc. Nordic Symp. Angina Pectoris, Göteborg, 1969 (in the press).
18.	Nordenfelt, I., Persson, S., and Redfors, A., Acta Med. Scand., 184, 465 (1968). | PubMed | ISI | ChemPort |