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Letters to Nature
Nature 222, 1292 - 1293 (28 June 1969); doi:10.1038/2221292a0

Growth of Human Foetal Tissue in Mice treated with Antilymphocyte Serum

B. PHILLIPS & J-C. GAZET

Surgical Unit, St George's Hospital Medical School, London SW1.

HETEROGRAFTS of human skin or tumour cell lines can be grown in the mouse using antilymphocyte serum (ALS) as immunosuppressant1,2. Human foetal tissue has been successfully grafted to rats treated with cortisone3. We have found that human foetal tissue will grow in mice thymectomized as adults and treated with ALS.

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References
1. Lance, E. M., and Medawar, P. B., Lancet, i, 1174 (1968). | Article | PubMed | ChemPort |
2. Phillips, B., and Gazet, J-C., Nature, 220, 1140 (1968). | PubMed | ISI | ChemPort |
3. Toolan, H. W., Proc. Soc. Exp. Biol. and Med., 86, 607 (1954). | ISI | ChemPort |
4. Sjodin, K., Dalmasso, A. P., Smith, J. M., and Martinez, C., Transplantation, 1, 521 (1963). | ISI |



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