Nature 222, 349 - 351 (26 April 1969); doi:10.1038/222349a0

Transfer of a Neomycin–Kanamycin Resistance Determinant by the F Factor of Escherichia coli K12

E. S. ANDERSON, JUNE N. MAYHEW & N. D. F. GRINDLEY

Enteric Reference Laboratory, Public Health Laboratory Service, Colindale Avenue, London NW9

In Escherichia coli K12 carrying both the F factor and a determinant for kanamycin resistance (K) the association of K with F appears to be independent of that of F with the chromosome. This applies equally to the extrachromosomal and the integrated states of the F factor.

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