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Genetics of Albumin Gainesville, a New Variant of Human Serum Albumin

Abstract

A β€œNEW” slow-moving variant of serum albumin has been found in members of a single family of Irish descent from the vicinity of Gainesville, Florida1. We have demonstrated that the electrophoretic mobility of albumin Gainesville is different from the mobilities of previously reported slow-moving albumins2–5, and have provided evidence to support the hypothesis of linkage between the albumin and Gc loci6,7.

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References

  1. Lau, T., and Sunderman, jun., F. W., Amer. J. Clin. Pathol., Abstr. (in the press).

  2. Melartin, L., Blumberg, B. S., and Lisker, R., Nature, 215, 1288 (1967).

    ArticleΒ  ADSΒ  CASΒ  Google ScholarΒ 

  3. Sandor, G., Martin, L., Porsin, M., Rousseau, A., and Martin, R., Nature, 208, 1222 (1965).

    ArticleΒ  ADSΒ  CASΒ  Google ScholarΒ 

  4. Robbins, J. L., Hill, G. A., Marcus, S., and Carlquist, J. H., J. Lab. Clin. Med., 62, 753 (1963).

    CASΒ  Google ScholarΒ 

  5. Weitkamp, L. R., Shreffler, D. C., Robbins, J. L., Drachmann, O., Adner, P. L., Wieme, R. J., Simon, N. M., Cooke, K. B., Sandor, G., Wuhrmann, F., Braend, M., and Tarnoky, A. L., Acta Genet., 17, 399 (1967).

    CASΒ  PubMedΒ  Google ScholarΒ 

  6. Weitkamp, L. R., Rucknagel, D. L., and Gershowitz, H., Amer. J. Human Genet., 18, 559 (1966).

    CASΒ  Google ScholarΒ 

  7. Kaarsalo, E., Melartin, L., and Blumberg, B. S., Science, 158, 123 (1967).

    ArticleΒ  ADSΒ  CASΒ  Google ScholarΒ 

  8. Williams, jun., F. G., in Serum Proteins and Dysproteinemias (edit. by Sunderman, F. W., and Sunderman, jun., F. W.), 125 (Lippincott, Philadelphia, 1964).

    Google ScholarΒ 

  9. Hirschfeld, J., Sci. Tools, 7, 18 (1960).

    CASΒ  Google ScholarΒ 

  10. Blumberg, B. S., and Riddel, N. M., J. Clin. Invest., 42, 867 (1963).

    ArticleΒ  CASΒ  Google ScholarΒ 

  11. Guy, L. R., Huestis, D. W., and Wilson, L. R., Technical Methods and Procedures of the American Association of Blood Banks, fourth ed., 51 (Amer. Assoc. Blood Banks, Chicago, 1966).

    Google ScholarΒ 

  12. Race, R. R., and Sanger, R., Blood Groups in Man, fourth ed., 416 (Black-well, Oxford, 1966).

    Google ScholarΒ 

  13. Finney, D. J., Ann. Eugen., 10, 12 (1935).

    Google ScholarΒ 

  14. Mohr, J., A Study of Linkage in Man, 19 (Munksgaard, Copenhagen, 1954).

    Google ScholarΒ 

  15. Haldane, J. B. S., and Smith, C. A. B., Ann. Eugen., 14, 10 (1947).

    ArticleΒ  CASΒ  Google ScholarΒ 

  16. Morton, N. E., Amer. J. Human Genet., 7, 277 (1955).

    CASΒ  Google ScholarΒ 

  17. Smith, C. A. B., Amer. J. Human Genet., 11, 289 (1959).

    CASΒ  Google ScholarΒ 

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LAU, T., SUNDERMAN, F., AGARWAL, S. et al. Genetics of Albumin Gainesville, a New Variant of Human Serum Albumin. Nature 221, 66–68 (1969). https://doi.org/10.1038/221066a0

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