Abstract
A βNEWβ slow-moving variant of serum albumin has been found in members of a single family of Irish descent from the vicinity of Gainesville, Florida1. We have demonstrated that the electrophoretic mobility of albumin Gainesville is different from the mobilities of previously reported slow-moving albumins2β5, and have provided evidence to support the hypothesis of linkage between the albumin and Gc loci6,7.
This is a preview of subscription content, access via your institution
Access options
Similar content being viewed by others
References
Lau, T., and Sunderman, jun., F. W., Amer. J. Clin. Pathol., Abstr. (in the press).
Melartin, L., Blumberg, B. S., and Lisker, R., Nature, 215, 1288 (1967).
Sandor, G., Martin, L., Porsin, M., Rousseau, A., and Martin, R., Nature, 208, 1222 (1965).
Robbins, J. L., Hill, G. A., Marcus, S., and Carlquist, J. H., J. Lab. Clin. Med., 62, 753 (1963).
Weitkamp, L. R., Shreffler, D. C., Robbins, J. L., Drachmann, O., Adner, P. L., Wieme, R. J., Simon, N. M., Cooke, K. B., Sandor, G., Wuhrmann, F., Braend, M., and Tarnoky, A. L., Acta Genet., 17, 399 (1967).
Weitkamp, L. R., Rucknagel, D. L., and Gershowitz, H., Amer. J. Human Genet., 18, 559 (1966).
Kaarsalo, E., Melartin, L., and Blumberg, B. S., Science, 158, 123 (1967).
Williams, jun., F. G., in Serum Proteins and Dysproteinemias (edit. by Sunderman, F. W., and Sunderman, jun., F. W.), 125 (Lippincott, Philadelphia, 1964).
Hirschfeld, J., Sci. Tools, 7, 18 (1960).
Blumberg, B. S., and Riddel, N. M., J. Clin. Invest., 42, 867 (1963).
Guy, L. R., Huestis, D. W., and Wilson, L. R., Technical Methods and Procedures of the American Association of Blood Banks, fourth ed., 51 (Amer. Assoc. Blood Banks, Chicago, 1966).
Race, R. R., and Sanger, R., Blood Groups in Man, fourth ed., 416 (Black-well, Oxford, 1966).
Finney, D. J., Ann. Eugen., 10, 12 (1935).
Mohr, J., A Study of Linkage in Man, 19 (Munksgaard, Copenhagen, 1954).
Haldane, J. B. S., and Smith, C. A. B., Ann. Eugen., 14, 10 (1947).
Morton, N. E., Amer. J. Human Genet., 7, 277 (1955).
Smith, C. A. B., Amer. J. Human Genet., 11, 289 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LAU, T., SUNDERMAN, F., AGARWAL, S. et al. Genetics of Albumin Gainesville, a New Variant of Human Serum Albumin. Nature 221, 66β68 (1969). https://doi.org/10.1038/221066a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/221066a0
This article is cited by
-
Classification of albumin and proalbumin genetic variants
La Ricerca in Clinica e in Laboratorio (1985)
-
Assignment of the structural gene coding for albumin to human chromosome 4
Human Genetics (1982)
-
Phenotype frequencies for four serum proteins in Afghanistan: Two ?new? albumin variants
Human Genetics (1972)
-
Another example of slow albumin allotype
Humangenetik (1971)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.