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Nature 220, 489 (02 November 1968); doi:10.1038/220489a0

Occurrence of Bufotenin in the Urine of Schizophrenic Patients and Normal Persons

ARILD FAURBYE & K. PIND

St Hans Hospital, Roskilde, Denmark.

BECAUSE of conflicting statements about the occurrence of bufotenin in the urine of schizophrenics and normal subjects1–13 we have now developed a method which allows semi-quantitative estimation of about 0.7 µg total bufotenin in 24 h urine samples. The method consists of purification and isolation by successive column chromatography, sublimation, paper chromatography and thin-layer chromatography.

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