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Nature 217, 615 - 617 (17 February 1968); doi:10.1038/217615a0

Size Changes in Isolated Nuclei of Amoeba proteus on Treatment with Polyionic Substances

W. KOROHODA, J. A. FORRESTER, K. G. MOREMAN & E. J. AMBROSE

Laboratory of Plant Physiology, Jagellonian University, Cracow
Chester Beatty Research Institute, Institute of Cancer Research: Royal Cancer Hospital, Fulham Road, London

Swelling of nuclei in Amoeba proteus is quite independent of the ionic strength of the medium or the osmolarity. Rather, it seems that surface charge is important in determining the configuration of a biological membrane which could give rise to large and specific changes in its permeability.

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