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Nature 216, 659-663 (18 November 1967) | doi:10.1038/216659a0; Received 26 September 1967

The Thymus and the Precursors of Antigen Reactive Cells

J. F. A. P. MILLER & G. F. MITCHELL

  1. The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria
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The thymus is important in providing an adequate pool of immunologically competent cells. Thymectomy does not reduce the number of precursor cells, but removes the influence necessary for their differentiation into antigen reactive cells.