Induction of Tumour Immunity with Tumour Cells treated with Extract of Garlic (Allium sativum)

Abstract

IT is generally believed that in some conditions tumour cells act antigenically, and that immunization of the host animal prevents tumour growth on subsequent challenge with virulent tumour cells. One of the most important problems in this field is to find a suitable and effective method to obtain attenuated tumour cells which still possess their antigenicity. Recently, two effective techniques were reported—the use of irradiated tumour cells¹ and the use of tumour cells treated with iodoacetate²—and Ishidate³ has used nitrogen mustard N-oxide for this purpose.