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Letters to Nature
Nature 214, 1020 - 1021 (03 June 1967); doi:10.1038/2141020a0

Development of Epileptic Seizures through Brain Stimulation at Low Intensity

GRAHAM V. GODDARD

Department of Psychology, University of Waterloo, Waterloo, Ontario, Canada.

A RECENT communication by Herberg and Watkins1 reported that animals are more resistant to convulsions shortly after having had a convulsion than at other times. This note does not debate this temporary elevation of convulsive threshold but rather emphasizes an equally important phenomenon in which, over a longer period of time, the convulsive threshold is reduced.

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References
1. Herberg, L. J., and Watkins, P. J., Nature, 209, 515 (1966). | PubMed | ISI | ChemPort |
2. Morrell, F., in Brain Mechanisms and Learning (edit. by Delafresnaye, J. F.) (Blackwell, Oxford, 1961).



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