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Article
Nature 214, 580-582 (6 May 1967) | doi:10.1038/214580a0; Received 23 January 1967
Lymphocytes in Congenital Absence of the Thymus
HAROLD W. LISCHNER, HOPE H. PUNNETT & ANGELO M. DiGEORGE
- Department of Pediatrics, Temple University School of Medicine and St. Christopher's Hospital for Children, Philadelphia 33, Pennsylvania
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Abstract
Lymphocytes of presumably extrathymic origin were obtained from an immunologically deficient child in whom there was complete failure of development of the thymus. They were poorly responsive to phytohaemagglutinin and to antigens, and responsiveness was not induced by incubation with thymic or transfer factors.
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