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Effect of Coffee and Tea on Serum Lipids in the Rat

Abstract

WE report experiments designed to distinguish the effects of the beverage and of sugar on the blood lipids of rats. Epidemiological investigations1,2 have already shown an association between ischaemic heart disease and the taking of coffee. Acute experiments in man and dogs3,4 indicate that caffeine produces a rise in free fatty acids in the blood, but no change in cholesterol or triglycerides. Our own investigations with patients5, however, suggest that the association of heart disease with coffee (or tea) is more likely to be caused by the sugar taken with the coffee or tea than by the caffeine they contain.

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AKINYANJU, P., YUDKIN, J. Effect of Coffee and Tea on Serum Lipids in the Rat. Nature 214, 426–427 (1967). https://doi.org/10.1038/214426b0

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  • DOI: https://doi.org/10.1038/214426b0

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