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Article
Nature 213, 862-865 (4 March 1967) | doi:10.1038/213862a0; Received 20 February 1967
Tertiary Structure of Ribonuclease
G. KARTHA, J. BELLO & D. HARKER
- Center for Crystallographic Research, Buffalo, New York
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Abstract
A model is proposed of the polypeptide chain in bovine pancreatic ribonuclease based on a 2 Å electron density map involving 7,294 reflexions and data from seven heavy atom derivatives. The molecule seems to be roughly kidney shaped with dimensions of about 38 
28 22 Å with a deep depression in the middle of one side. The model disagrees with that based on a 5.5 Å map suggested by Dr. C. H. Carlisle et al. (Nature, 213, 557; 1967).
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