Nature 209, 1349 (26 March 1966); doi:10.1038/2091349a0

Activity of Lysosomal Enzymes in White Muscle Disease

I. D. DESAI

Department of Biochemistry, Faculty of Medicine, University of British Columbia, Vancouver.

DEFICIENCY of selenium and vitamin E in the diet of late-gestation ewes is known to cause white muscle disease (WMD) in lambs^1,2. It is generally characterized by degenerative changes in skeletal and cardiac muscles. Since the myopathy is prenatally influenced, the development of the disease presumably has a direct relationship with the deprivation of protectors essential for the prevention of nutritional muscular dystrophy.

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