Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Antiviral Action of Oxidized Spermine— Inactivation of Plant Viruses

Abstract

SPERMINE, NH2(CH2)3NH(CH2)4NH(CH2)3NH2, a naturally occurring polyamine, is oxidized by purified serum amine oxidase as follows (ref. 1):

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Tabor, C. W., Tabor, H., and Bachrach, U., J. Biol. Chem., 239, 2194 (1964).

    CAS  Google Scholar 

  2. Hirsch, J. G., J. Exp. Med., 97, 327 (1953).

    Article  CAS  Google Scholar 

  3. Fletcher, F., Eptstein, C., and Jewell, P. I., J. Gen. Microbiol., 8, 323 (1953).

    Article  CAS  Google Scholar 

  4. Tabor, C. W., and Rosenthal, S. M., J. Pharmacol. Exp. Therap., 116, 139 (1956).

    CAS  Google Scholar 

  5. Bachrach, U., and Persky, S., J. Gen. Microbiol., 37, 195 (1964).

    Article  CAS  Google Scholar 

  6. Bachrach, U., Tabor, C. W., and Tabor, H., Biochim. Biophys. Acta, 78, 768 (1963).

    Article  CAS  Google Scholar 

  7. Corbett, M. K., Virology, 15, 8 (1961).

    Article  CAS  Google Scholar 

  8. Steere, R. L., Adv. Virus Res., 6, 1 (1959).

    Article  ADS  CAS  Google Scholar 

  9. Siegel, S., Nonparametric Statistics, pp. 68–75 (McGraw Hill, New York, 1956).

    Google Scholar 

  10. Bachrach, U., and Leibovici, J., Proc. Sixth Intern. Congr. Biochem., 32, 42 (1964).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

BACHRACH, U., RABINA, S., LOEBENSTEIN, G. et al. Antiviral Action of Oxidized Spermine— Inactivation of Plant Viruses. Nature 208, 1095–1096 (1965). https://doi.org/10.1038/2081095a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2081095a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing