Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Hydrolysis of Disaccharides during Absorption by the Perfused Small Intestine of Amphibia

Nature volume 208, pages 1097–1098 (1965)Cite this article

Abstract

ALTHOUGH it is now generally conceded, that disaccharides may be absorbed intact at appreciable rates from the lumen of the small intestine, as found for maltose by Waymouth Reid in 1901, very little is known about the factors which affect the process. It is established that in mammals, including human subjects, disaccharides such as lactose, sucrose and maltose undergo hydrolysis at some site in or on the mucosal cells and not in the intestinal lumen1–4. We have now investigated the absorption of some disaccharides by the small intestine of some Amphibia using a system for the perfusion of the mesenteric vascular bed.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Reid, E. W., J. Physiol., 26, 427 (1901).

    Article  CAS  Google Scholar 

  2. Cajori, F. A., Amer. J. Physiol., 104, 659 (1933).

    CAS  Google Scholar 

  3. Miller, D., and Crane, R., Biochem. Biophys. Acta, 52, 281 (1961).

    Article  CAS  Google Scholar 

  4. Chain, E. B., Mansford, K. R. L., and Pocchiari, F., J. Physiol., 154, 39 (1960).

    Article  CAS  Google Scholar 

  5. Fisher, R. B., and Parsons, D. S., J. Physiol., 110, 36 (1949).

    Article  CAS  Google Scholar 

  6. Dahlqvist, A., Anal. Biochem., 7, 18 (1964).

    Article  CAS  Google Scholar 

  7. Miller, D., and Crane, R., Biochim. Biophys. Acta, 52, 293 (1961).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, University of Oxford,

    D. S. PARSONS & J. S. PRICHARD

Authors
  1. D. S. PARSONS
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. S. PRICHARD
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

PARSONS, D., PRICHARD, J. Hydrolysis of Disaccharides during Absorption by the Perfused Small Intestine of Amphibia. Nature 208, 1097–1098 (1965). https://doi.org/10.1038/2081097a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2081097a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing