Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Advances in Liquid Chromatography

Abstract

THE development of liquid chromatographic techniques has been restricted because of the non-existence of sensitive detection systems. Apart from the tedious manual analysis of evaporation and determination by weight or titration the only available continuous method has been ultra-violet absorption. In this process, the sample, for example amino-acid, peptide or protein, is developed by an external reagent like ninhydrin to give strong absorption in the ultra-violet. This procedure is carried out at a single wave-length and is restricted to those samples with the required characteristic.

This is a preview of subscription content, access via your institution

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. U.K. Patent, No. 998, 107.

  2. Chem. and Indust., 746 (May 1964).

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

MAKIN, B., SPEAKMAN, F. Advances in Liquid Chromatography. Nature 208, 1087–1088 (1965). https://doi.org/10.1038/2081087a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/2081087a0

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing