Nature 202, 1122 - 1123 (13 June 1964); doi:10.1038/2021122a0

Identification of the Predicted Blood Group Antibody Anti-Yt^b

CAROLYN M. GILES & M. N. METAXAS

Medical Research Council Blood Group Reference Laboratory, London.
Swiss Research Council Blood Transfusion Centre, Zurich.

EATON et al. ¹ described a new blood group antibody, anti-Yt^a, which reacted with a very high proportion of blood samples (99.6 per cent) by the anti-human globulin technique. The antibody was shown to distinguish between homozygous Yt ^a Yt ^b samples and heterozygous Yt ^a Yt ^a samples by giving a dosage effect, and so it was possible to estimate the gene frequencies of both Yt ^a (93.8 per cent) and the postulated Yt ^b (6.2 per cent).

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