Abstract
IN order to test the activity of teratogenic drugs in embryonic vegetal tissues, we have examined mitoses of plant cells which proliferate rapidly, such as those present in radical apices of Liliaceae, in the presence of a compound with a proved action on man (α-(N-phthalimido) glutarimide (thalidomide))1. The biological material used for these experiments was the common onion (Allium cepa} in the root apical cells of which the mitotic frequency is high and the figures show up clearly.
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References
Taussig, Helen B., and Baltimore, M. D., J. Amer. Med. Assoc., 180, 1106 (1962).
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GIACOMELLO, G., MALATESTA, P. & QUAGLIA, G. Action of Thalidomide on Radical Meristems of Allium cepa. Nature 201, 940–941 (1964). https://doi.org/10.1038/201940a0
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DOI: https://doi.org/10.1038/201940a0
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