Nature 199, 190 - 191 (13 July 1963); doi:10.1038/199190b0

Pinealoma : a Variety of Argentaffinoma?

ISAAC COSTERO, ROSARIO BARROSO-MOGUEL & KENNETH M. EARLE

National Institute of Cardiology, Department of Pathology, Mexico City, Mexico.
Armed Forces Institute of Pathology, Washington, D.C.

SEROTONIN (5-hydroxytryptamine) contained in the gastrointestinal tract is intimately associated with the Kultschitzky type of cells¹. Carcinoid tumours arise from such cells so their serotonin content is very important²; apparently, the majority, or maybe all, the symptoms of the so-called carcinoid syndrome must be attributed to the presence of serotonin at the level of the tumour³.

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