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| Nature 197, 1210 (23 March 1963); doi:10.1038/1971210a0 |
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Stimulation of Secretion of Insulin by Adenosine-triphosphate
J. L. R-CANDELA & M. C. GARCIA-FERNANDEZ
Instituto 'G. Marañon', Velazquez 138, Madrid, 6.
IN previous papers1–4 we showed that different metabolites, both in vivo and in vitro, produce insulin secretion which we measured by the method of the epididymal fat of the rat. In view of some of these results we decided to ascertain whether the intravenous injection of ATP was a stimulant to insulin secretion; although we are aware that the point of view actually held is that the metabolic processes affected by this nucleotide are intracellular.
- R-Candela, J. L. , and R-Candela, R. , Proc. Third Cong. International Diabetes Federation, Dusseldorf, 762 (July 1958).
- Garcia-Fernandez, M. C. , R-Candela, J. L. , and R-Candela, R. , Biochim. Biophys. Acta (in the press).
- Castrillon, A. M. , Garcia-Fernandez, M. C. , R-Candela, R. , and R-Candela, J. L. , Proc. Soc. Exp. Biol. and Med., 109, 172 (1962). | ISI | ChemPort |
- R-Candela, J. L. , R-Candela, R. , Martin-Hernandez, D. , and Castilla-Cortazar, T. , Nature, 195, 711 (1962). | Article | PubMed |
© 1963 Nature Publishing Group
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