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Letters to Nature
Nature 186, 647 - 648 (21 May 1960); doi:10.1038/186647a0

Changes in the Deoxyribonucleic Acid Content of Mouse Sarcoma 37 Cells following Serial Irradiation

A. E. G. PEARSON & N. B. ATKIN

Department of Experimental Pathology, Mount Vernon Hospital, North wood, Middlesex.

CHANGES in the deoxyribonucleic acid content of human tumour cells following irradiation have been reported by Richards and Atkin1 and Atkin, Richards and Ross2. There exists strong evidence in support of a positive relationship between modal deoxyribonucleic acid content and the degree of ploidy ; this has been discussed by Atkin and Richards3, and Richards and Atkin4. This communication reports changes in content of deoxyribonucleic acid in the mouse sarcoma 37 following serial irradiation.

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References
1. Richards, B. M., and Atkin, N. B., Brit. J. Cancer, 13, 788 (1959). | ISI | ChemPort |
2. Atkin, N. B., Richards, B. M., and Ross, A. J., Brit. J. Cancer, 13, 773 (1959). | PubMed | ISI | ChemPort |
3. Atkin, N. B., and Richards, B. M., Brit. J. Cancer, 10, 769 (1956). | PubMed | ISI | ChemPort |
4. Richards, B. M., and Atkin, N. B., Acta Int. Unio contra Cancrum, 16, 124 (1960). | ChemPort |
5. Pearson, A. E. G., Brit. J. Cancer, 13, 477 (1959). | PubMed | ISI | ChemPort |



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