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Letters to Nature
Nature 185, 117 - 118 (09 January 1960); doi:10.1038/185117a0

Hydrophilic Gels for Biological Use

O. WICHTERLE & D. LÍM

Institute for Macromolecular Chemistry, Czechoslovak Academy of Sciences, Prague.

PLASTICS to-day enjoy wide use in many fields, and it is natural that the possibility of their employment in permanent contact with living tissues has been seriously considered. A study of the literature shows that almost all known plastics have been proposed for this purpose at various times. The question of structural similarity with the tissue has not, however, been emphasized although physiologically unfavourable effects were observed in most cases of application of normal type plastics.



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