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Nature 178, 308 - 309 (11 August 1956); doi:10.1038/178308a0

Isotopes incorporated in the Nucleic Acids of Trypanosoma mega

G. J. BONÉ & M. STEINERT

Institut pour la Recherche Scientifique en Afrique Centrale, Centre de Recherche du Katanga, Elisabethville, Congo Belge. March 27.

THE trypanosomes can be cultured in media containing nucleic acids or purines. Crithidia fasciculata grows in a synthetic medium with folic acid, guanine or guanosine1,2. Trypanosoma cruzi has been cultured by Citri and Grossowicz3 in a defined medium enriched with ribonucleic acid, and its growth is stimulated by guanosine. T. rhodesiense seems to need adenine and adenosine as growth factors4.

  1. Cowperthwaite, J. , Weber, M. M. , Packer, L. , and Hutner, S. H. , Ann. New York Acad. Sci., 56, 972 (1953). | ISI | ChemPort |
  2. Nathan, H. A. , and Cowperthwaite, J. , Proc. Soc. Exp. Biol. Med., 85, 117 (1954). | PubMed | ISI | ChemPort |
  3. Citri, N. , and Grossowicz, N. , J. Gen. Microbiol., 13, 273 (1955). | PubMed | ISI | ChemPort |
  4. Williamson, J. , and Rollo, I. M. , Nature, 170, 376 (1952). | Article | PubMed | ISI | ChemPort |
  5. Laveran, A. , and Mesnil, F. , in "Trypanosomes et Trypanosomiases" (Masson, Paris, 1912).
  6. Steinert, M. , Biochim. Biophys. Acta, 18, 511 (1955). | Article | PubMed | ISI | ChemPort |



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