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Letters to Nature
Nature 168, 654 (13 October 1951); doi:10.1038/168654a0

Action of Terramycin and Chloromycetin on Cholera Vibrio in Mice

E. OLEJNIK & S. DAVIDOVITCH

Microbiological Laboratories, Weizmann Institute of Science, Rehovoth, Israel. May 20.

TERRAMYCIN HYDROCHLORIDE (Pfizer) was tested in mice inoculated with Vibrio cholera. The animals were inoculated intraperitoneally with a suspension of 1 ml. of an 18-hr, old culture; the suspension contained 50 times 106 organisms per ml. and 5 per cent mucin (Armour)1. These inoculations were fatal in 48 hr. Four strains (Ogawa 41, Inaba 35 and 29, and a Mediterranean Inaba strain) were employed.

  1. Griffits, Y. Y. , Public Health Reports, 57, 707 (1942).
  2. Gauld, R. L. , Schlingman, A. S. , Jackson, E. B. , Manning, M. C. , Batson, H. C. , and Cambell, Ch. C. , J. Bact., 57, 349 (1949). | PubMed | ISI |



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