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Nature 165, 191 - 192 (04 February 1950); doi:10.1038/165191a0

Uridine Diphosphate Glucose: the Coenzyme of the Galactose–Glucose Phosphate Isomerization

C. E. CARDINI, A. C. PALADINI, R. CAPUTTO & L. F. LELOIR

Instituto de Investigaciones Bioquímicas, Fundación Campomar, Julián Alvarez 1719, Buenos Aires. Aug. 27.

A PREVIOUS report1 dealt with the enzymatic conversion of galactose-1-phosphate into glucose-1-phosphate and mentioned that a thermostable factor is necessary for the reaction. This factor has now been obtained practically pure, and for reasons given below will be referred to as uridine diphosphate glucose.

  1. Caputto, R. , Leloir, L. F. , Trucco, R. E. , Cardini, C. E. , and Paladini, A. C. , J. Biol. Chem., 179, 497 (1949). | ISI | ChemPort |
  2. Ploeser, J. McT. , and Loring, H. S. , J. Biol. Chem., 178, 431 (1949). | ISI | ChemPort |
  3. Gurin, s , and Hood, D. B. , J. Biol. Chem., 131, 211 (1939). | ChemPort |
  4. Gulland, J. M. , and Smith, H. , J. Chem. Soc., 338 (1947).
  5. Massart, L. , and Hoste, J. , Biochim. et Biophys. Acta, 1, 83 (1947). | Article | ISI | ChemPort |
  6. Park, J. T. , and Johnson, M. J. , J. Biol. Chem., 179, 585 (1949). | ISI | ChemPort |



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