nature 164, 235-236 (06 August 1949) | doi:10.1038/164235b0

Cultivation of Foot-and-Mouth Disease Virus in Explanted Epithelial Tissue of the Bovine Rumen

H. S. FRENKEL &  H. H. J. FREDERIKS

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FOR the preparation of vaccine against foot-and-mouth disease a source of the causative agent is needed. This source can be the living susceptible animal; or it can be the artificially cultivated virus, provided that a sufficient quantity of this agent can be produced.

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References

  1. Maitland, M. C., and Maitland, H. B., 4th Progress Keport of the Foot-and-Mouth Disease Research Committee.
  2. Hecke, F., Z. Bakt., 128, 336 (1933).
  3. Frenkel and van Waveren, "Algemeene Landsdrukkery" (The Hague, 1934–35).
  4. Frenkel, H. S., Office International des Epizootics, 28 (1947).
  5. See Parker, "Methods of Tissue Culture", 76 (Paul Boeber, Inc.).

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