Letters to Editor
nature 143, 942-943 (03 June 1939) | doi:10.1038/143942c0
Temperature Activation of the Urease-Urea System
IRWIN W. SIZER
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THE activity of several enzymes (for examples yeast and malt invertase1, and E. coli dehydrogenases2) has been shown to increase exponentially with temperature according to the Arrhenius equation, where K is the rate, Z is a constant, e is 2.718, R is the gas constant, T the absolute temperature, and μ the energy of activation of the reaction in calories per gm. mol.
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References
- Sizer, I. W., J. Cell. and Comp. Physiol., 10, 79 (1937); Enzymologia, 4, 215 (1938).
- Gould, B. S., and Sizer, I. W., J. Biol. Chem., 124, 269 (1938).
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- Hellerman, L., Perkins, M., and Clark, W. M., Proc. Nat. Acad. Sci., 19, 855 (1933).
- Euler, H., “Chemie der Enzyme”, Teil 1 (1920).
- Van Slyke, D. D., and Cullen, G. E., J. Biol. Chem., 19, 141 (1914).
