Nature 135, 510-510 (30 March 1935) | doi:10.1038/135510a0

Experimental Induction of Coupling in Xenopus laevis, with the Production of Fertilised Eggs



IN the course of an investigation into the sexual cycle of Xenopus laevis, the South African clawed toad (Shapiro and Zwarenstein1, Shapiro and Shapiro2), certain outstanding differences in the sexual behaviour of this amphibian were observed under laboratory conditions as compared with natural conditions prevailing in the pond. It was noticed, among other things, that mating activity was never in any circumstances exhibited in captivity in the laboratory even at the height of the breeding season (July to September in South Africa).



  1. Shapiro and Zwarenstein, J. Exp. Biol, 10, 4, 372; 1933.
  2. Shapiro and Shapiro, J. Exp. Biol., 11, 1, 73; 1934. | ChemPort |
  3. Katzman and Doisy, J. Biol. Chem., 744; 1932.
  4. Hogben and Slome, Proc. Roy. Soc., B, 108, 10; 1931.