Abstract
GENETICS and cytology prove that the sex of the progeny of mammals depends upon the sex of the spermatozoon fertilising the ovum ; the ovum itself is not determined as to sex. The ‘female’ spermatozoon possesses an X-chromosome, the male possesses a Y-chromosome (or no sex chromosome at all), while every ovum has an X-chromosome. Male-determining and female-determining spermatozoa are mixed irregularly in the sperm. Therefore there is only one way of controlling the sex of progeny in mammals, namely, by separating the male-determining from the female-determining spermatozoa.
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KOLTZOFF, N., SCHRÖDER, V. Artificial Control of Sex in the Progeny of Mammals. Nature 131, 329 (1933). https://doi.org/10.1038/131329a0
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DOI: https://doi.org/10.1038/131329a0
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