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The ENCODE project — standing for ENCyclopedia Of DNA Elements — has set out to identify all the functional elements in the human genome. Detailed in the 14 June 2007 issue of Nature, a pilot project on 1% of the genome reveals new insights about how the information coded in the DNA blueprint is turned into functioning systems in the living cell.
Poster
This poster graphically displays some of the experimental results for 500,000 base pairs of sequence, in part of one of the 44 ENCODE regions spread around the genome.
Current Research
ARTICLE
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project Free access
The ENCODE Project Consortium
Nature 447, 799—816 (14 June 2007) doi:10.1038/nature05874
Abstract | Full Text | PDF | Supplementary Information
NEWS AND VIEWS
Genomics: Encyclopaedia of humble DNA
Greally JM
Nature 447, 782—783 (14 June 2007) doi:10.1038/447782a
NEWS
Genome project turns up evolutionary surprises
Check E
Nature 447, 760—761 (14 June 2007) doi:10.1038/447760a
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Related papers in Genome Research
Top of pageLinks
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Archive
ARTICLE
Initial sequencing and analysis of the human genome
International Human Genome Sequencing Consortium
Nature 409, 860—921 (15 February 2001)
Abstract | Full Text | PDF | Supplementary Information
LETTER
Comparative analyses of multi-species sequences from targeted genomic regions
Thomas JW et al.
Nature 424, 788—793 (14 August 2003) doi:10.1038/nature01858
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
DNase-chip: a high-resolution method to identify DNase I hypersensitive sites using tiled microarrays
Crawford GE et al.
Nature Methods 3, 503—509 Published online 21 June 2006 doi:10.1038/nmeth888
Abstract | Full Text | PDF | Supplementary Information
LETTER
Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF
Iver VR et al.
Nature 409, 533—538 (25 January 2001) doi:10.1038/35054095
Abstract | Full Text | PDF | Supplementary Information
ARTICLE
Genome-scale mapping of DNase I sensitivity in vivo using tiling DNA microarrays
Sabo PJ et al.
Nature Methods 3, 511—518 Published online 21 June 2006 doi:10.1038/nmeth890
Abstract | Full Text | PDF | Supplementary Information
REVIEW
Genome-wide transcription and the implications for genomic organization
Kapranov P, Willingham AT and Gingeras TR
Nature Reviews Genetics 8, 413—423 (June 2007) doi:10.1038/nrg2083
LETTER
Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing
Schübeler D et al.
Nature Genetics 32, 438—442 Published online 30 September 2002 doi:10.1038/ng1005
Abstract | Full Text | PDF | Supplementary Information
COMMENTARY
DNA replication timing: random thoughts about origin firing
Rhind N
Nature Cell Biology 8, 1313—1316 (December 2006) doi:10.1038/ncb1206-1313
NEWS FEATURE
Genetics: What is a gene?
Pearson H
Nature 441, 398—401 (25 May 2006) Published online 24 May 2006 doi:10.1038/441398a





