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Dictyostelium discoideum genome
In this focus
The slime mould Dictyostelium discoideum has been an important laboratory model for over 50 years. These social amoebae normally live in forest soil where they hunt bacteria and yeast, and have therefore excelled in studies of how cells sense and move towards attractants in their environment. When hunting is not successful, the unicellular organisms become one multicellular entity and form a fruiting body to disperse spores, shown on the cover image. Here, Nature presents analysis of the genome and proteome of Dictyostelium, available free. We also provide an archive of related papers and links to major Dicty resources.
Current research articles
The genome of the social amoeba Dictyostelium discoideum Free access
Eichinger L., et al.
Nature 435, 43-57 (4 May 2005) doi:10.1038/nature03481
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Epistasis analysis with global transcriptional phenotypes.
Van Driessche N. et al.
Nature Genetics 37, 471-477 (10 Apr 2005) doi:10.1038/ng1545
Pleiotropy as a mechanism to stabilize cooperation.
Foster K. R., Shaulsky G., Strassmann J. E., Queller D. C. & Thompson C. R.
Nature 431, 693-696 (7 Oct 2004) doi:10.1038/nature02894
Functions of LIM proteins in cell polarity and chemotactic motility.
Khurana B., Khurana T., Khaire N. & Noegel A.A.
EMBO J. 21, 5331-5342 (15 Oct 2002) doi:10.1093/emboj/cdf550
Sequence and analysis of chromosome 2 of Dictyostelium discoideum Free access
Glockner G. et al.
Nature 418, 79-85 (04 Jul 2002) doi:10.1038/nature00847
A common mechanism of action for three mood-stabilizing drugs.
Williams R.S.B., Cheng L., Mudge A.W. & Harwood A.J.
Nature 417, 292-295 (16 May 2002) doi:10.1038/417292a
Altruism and social cheating in the social amoeba Dictyostelium discoideum.
Strassmann J.E., Zhu Y. & Queller D.C.
Nature 408, 965-967 (21 Dec 2000) doi:10.1038/35050087
Ca2+ signalling is not required for chemotaxis in Dictyostelium.
Traynor D., Milne J.L.S., Insall R.H. & Kay R.R.
EMBO J. 19, 4846-4854 (01 Sep 2000) doi:10.1093/emboj/19.17.4846
A new anatomy of the prestalk zone in Dictyostelium.
Roos W., Scheidegger C. & Gerish G.
Nature 340, 144-146 (13 Jul 1989) doi:10.1038/340144a0
Adenylate cyclase activity oscillations as signals for cell aggregation in Dictyostelium discoideum.
Roos W., Scheidegger C. & Gerish G.
Nature 266, 259-261 (1977)
Cell differentiation without morphogenesis in Dictyostelium discoideum.
Town C.D., Gross J.D. & Kay R.R.
Nature 262, 717-719 (1976)
Synthesis of cyclic AMP in Dictyostelium discoideum and Polysphondylium pallidum.
Konijn T.M., Chang Y.Y. & Bonner J.T.
Nature 224, 1211-1212 (1969)
Top of pageWeb links
- dictyBase
- Dicty cDNA Project, Japan
- Dicty Ensembl
- Dicty Workbench
- Entrez Genome
- NIH Dicty Resource Page
- Baylor College of Medicine
- Institute for Molecular Biology, Jena
- University of Cologne
- Wellcome Trust Sanger Institute
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