Nature web focus: Cell cycle and cell division

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	Friday 23 March 2018
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The regulation of cell cycle progression and cell division is at the heart of cell biological research. Understanding the basic mechanisms of cell division also offers new insights into cancer biology. Gathered here is a selection of recent research and comment in this area of research published in the pages of Nature, including groundbreaking research from today's issue. This focus also includes our recent Nature Insight Cell division and Cancer.

RESEARCH
Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry
Michael Rape & Marc W. Kirschner
Nature 432, 588–595 (2 Dec 2004)

Poly(ADP-ribose) is required for spindle assembly and structure
Paul Chang, Myron K. Jacobson & Timothy J. Mitchison
Nature 432, 645–649 (2 Dec 2004)

NEWS AND VIEWS
Cell division: The heart of the cycle
Lukas J. & Bartek J.
Nature 432, 564–567 (2 Dec 2004)

Cytoskeleton: Spindle saga
Karsenti E.
Nature 432, 563–564 (2 Dec 2004)

NATURE INSIGHT
Cell division and cancer
Nature 432, November 2004

All the latest cell and molecular biology news

LETTERS TO NATURE

Phosphorylation-dependent binding of mitotic cyclins to Cdc6 contributes to DNA replication control
Satoru Mimura et al.
Nature 431, 1118–1123 (28 Oct 2004)

A microtubule-binding myosin required for nuclear anchoring and spindle assembly
Kari L. Weber et al.
Nature 431, 325–329 (16 Sep 2004)

NEWS AND VIEWS

Cell biology: Myosins meet microtubules
Margaret A. Titus
Nature 431, 252–253 (16 Sep 2004)

LETTERS TO NATURE

Centrosomes direct cell polarity independently of microtubule assembly in C. elegans embryos
Carrie R. Cowan & Anthony A. Hyman
Nature 431, 92–96 (02 Sep 2004)

Separase-mediated cleavage of cohesin at interphase is required for DNA repair
Koji Nagao, Yoh Adachi & Mitsuhiro Yanagida
Nature 430, 1044–1048 (26 Aug 2004)

Cell cycle regulation of central spindle assembly
Masanori Mishima et al.
Nature 430, 908–913 (19 Aug 2004)

NEWS AND VIEWS

Cell division: Timing the machine
Bruce Bowerman
Nature 430, 840–842 (19 Aug 2004)

LETTERS TO NATURE

Structural basis for inhibition of the replication licensing factor Cdt1 by geminin
Changwook Lee et al.
Nature 430, 913–917 (19 Aug 2004)

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control
Eva Hernando et al.
Nature 430, 797–802 (12 Aug 2004)

Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation
Ying Gong, Chunhui Mo & Scott E. Fraser
Nature 430, 689–693 (05 Aug 2004)

LETTERS TO NATURE

Cohesin relocation from sites of chromosomal loading to places of convergent transcription
Armelle Lengronne et al.
Nature 430, 573–578 (29 Jul 2004)

NEWS AND VIEWS

Molecular biology: Cohesins slip sliding away
Karen E. Ross & Orna Cohen-Fix
Nature 430, 520–521 (29 Jul 2004)

LETTERS TO NATURE

First cleavage plane of the mouse egg is not predetermined but defined by the topology of the two apposing pronuclei
Takashi Hiiragi & Davor Solter
Nature 430, 360–364 (15 Jul 2004)

NEWS AND VIEWS

Embryology: Plane talk
Gerald Schatten & Peter Donovan
Nature 430, 301–302 (15 Jul 2004)

LETTERS TO NATURE

Cyclin-dependent kinases regulate the antiproliferative function of Smads
Isao Matsuura et al.
Nature 430, 226–231 (08 Jul 2004)

Cdc42 and mDia3 regulate microtubule attachment to kinetochores
Shingo Yasuda et al.
Nature 428, 767–771 (15 Apr 2004)

Control of the SCF^Skp2-Cks1 ubiquitin ligase by the APC/C^Cdh1 ubiquitin ligase
Tarig Bashir et al.
Nature 428, 190–193 (11 Mar 2004)

Degradation of the SCF component Skp2 in cell-cycle phase G1 by the anaphase-promoting complex
Wenyi Wei et al.
Nature 428, 194–198 (11 Mar 2004)

Tension between two kinetochores suffices for their bi-orientation on the mitotic spindle
Hilary Dewar et al.
Nature 428, 93–97 (04 Mar 2004)

NEWS AND VIEWS

Cell division: Feeling tense enough?
Iain M. Cheeseman & Arshad Desai
Nature 428, 32–33 (04 Mar 2004)

ARTICLE

The conserved kinetochore protein shugoshin protects centromeric cohesion during meiosis
Tomoya S. Kitajima, Shigehiro A. Kawashima & Yoshinori Watanabe
Nature 427, 510–517 (05 Feb 2004) Nature AOP published online

NEWS AND VIEWS

Cell division: Guardian spirit blesses meiosis
Robin Allshire
Nature 427, 495–497 (05 Feb 2004)

LETTERS TO NATURE

Two mitotic kinesins cooperate to drive sister chromatid separation during anaphase
Gregory C. Rogers et al.
Nature 427, 364–370 (22 Jan 2004)

NEWS AND VIEWS

Cell division: Burning the spindle at both ends
Rebecca W. Heald
Nature 427, 300–301 (22 Jan 2004)