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  Dolly, the world's first animal to be cloned from an adult cell, died last week. Suffering from progressive lung disease at the age of just six years old, she was put down at the Roslin Institute in Edinburgh where she was created. In this special web focus, Nature reflects on the life of this extraordinary sheep, and presents an archive of articles and papers from the Nature family of journals, including original papers, news and features.

NEWS
Dolly's death leaves researchers woolly on clone ageing issue

NATURE SCIENCE UPDATE
Obituary: Dolly the Sheep

Celebrity clone dies of drug overdose


NEWS & FEATURES
The health profile of cloned animals
Jose B. Cibelli, Keith H. Campbell, George E. Seidel, Michael D. West, Robert P. Lanza
Nature Biotechnology 20, 13–14 (01 Jan 2001)

Cloning's owners go to war
The team that created Dolly the sheep captured the headlines, but several groups now have patents on cloning. Peter Aldhous considers how this tangled web of proprietary claims will affect the future of the technology.
Nature 405, 610–612 (08 Jun 2000)

Dolly is a clone – and no longer alone
After the furore that surrounded the arrival of Dolly, the first mammal to be cloned from differentiated adult cells, doubts were raised that she really was a clone. Those doubts can now be set aside, and the technique has been further validated by the cloning of mice.
Davor Solter
Nature 394, 315–316 (08 Jun 2000)

RESEARCH
Viable offspring derived from fetal and adult mammalian cells
Wilmut, I., Schnieke, A.E., McWhir, J., Kind, A.J. & Campbell K.H.S
Nature 385, 810–813 (27 Feb 1997)

Early death of mice cloned from somatic cells
Narumi Ogonuki, et al.
Nature Genetics 30, 253–254 (01 Mar 2002)

Mitochondrial DNA genotypes in nuclear transfer-derived cloned sheep
Matthew J. Evans, Cagan Gurer, John D. Loike, Ian Wilmut, Angelika E. Schnieke, Eric A. Schon
Nature Genetics 23, 90–93 (01 Sep 1999)

Full-term development of mice from enucleated oocytes injected with cumulus cell nuclei
T. Wakayama, A. C. F. Perry, M. Zuccotti, K. R. Johnson, R. Yanagimachi
Nature 394, 369–374 (23 Jul 1998)

 

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