Nature Nature is the foremost international weekly scientific journal in the world and is the flagship journal for Nature Portfolio. It publishes the finest peer-reviewed research in all fields of science and technology on the basis of its originality, importance, interdisciplinary interest, timeliness, accessibility, elegance and surprising conclusions. Nature publishes landmark papers, award winning news, leading comment and expert opinion on important, topical scientific news and events that enable readers to share the latest discoveries in science and evolve the discussion amongst the global scientific community. http://feeds.nature.com/nature/rss/current Nature Publishing Group en © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Nature © 2024 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. permissions@nature.com Nature https://www.nature.com/uploads/product/nature/rss.png http://feeds.nature.com/nature/rss/current <![CDATA[Structural insights into vesicular monoamine storage and drug interactions]]> https://www.nature.com/articles/s41586-024-07290-7 Nature, Published online: 18 March 2024; doi:10.1038/s41586-024-07290-7

Structural insights into vesicular monoamine storage and drug interactions]]>
Jin YeHuaping ChenKaituo WangYi WangAaron AmmermanSamjhana AwasthiJinbin XuBin LiuWeikai Li doi:10.1038/s41586-024-07290-7 Nature, Published online: 2024-03-18; | doi:10.1038/s41586-024-07290-7 2024-03-18 Nature 10.1038/s41586-024-07290-7 https://www.nature.com/articles/s41586-024-07290-7
<![CDATA[Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma]]> https://www.nature.com/articles/s41586-024-07277-4 Nature, Published online: 18 March 2024; doi:10.1038/s41586-024-07277-4

Author Correction: An atlas of epithelial cell states and plasticity in lung adenocarcinoma]]>
Guangchun HanAnsam SinjabZahraa RahalAnne M. LynchWarapen TreekitkarnmongkolYuejiang LiuAlejandra G. SerranoJiping FengKe LiangKhaja KhanWei LuSharia D. HernandezYunhe LiuXuanye CaoEnyu DaiGuangsheng PeiJian HuCamille AbayaLorena I. Gomez-BolanosFuduan PengMinyue ChenEdwin R. ParraTina CasconeBoris SepesiSeyed Javad MoghaddamPaul ScheetMarcelo V. NegraoJohn V. HeymachMingyao LiSteven M. DubinettChristopher S. StevensonAvrum E. SpiraJunya FujimotoLuisa M. SolisIgnacio I. WistubaJichao ChenLinghua WangHumam Kadara doi:10.1038/s41586-024-07277-4 Nature, Published online: 2024-03-18; | doi:10.1038/s41586-024-07277-4 2024-03-18 Nature 10.1038/s41586-024-07277-4 https://www.nature.com/articles/s41586-024-07277-4
<![CDATA[I study small organisms to tackle big climate problems]]> https://www.nature.com/articles/d41586-024-00820-3 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00820-3

Marine biologist Gabriel Renato Castro cultivates compounds from cyanobacteria to support agriculture and the environment.]]>
Nikki Forrester doi:10.1038/d41586-024-00820-3 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00820-3 2024-03-18 Nature 10.1038/d41586-024-00820-3 https://www.nature.com/articles/d41586-024-00820-3
<![CDATA[Are we all doomed? How to cope with the daunting uncertainties of climate change]]> https://www.nature.com/articles/d41586-024-00790-6 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00790-6

It’s easy to feel overwhelmed when thinking about the damage that might be wrought by global warming — but that is missing the point.]]>
Adam Sobel doi:10.1038/d41586-024-00790-6 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00790-6 2024-03-18 Nature 10.1038/d41586-024-00790-6 https://www.nature.com/articles/d41586-024-00790-6
<![CDATA[Four years on: the career costs for scientists battling long COVID]]> https://www.nature.com/articles/d41586-024-00819-w Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00819-w

Many with the condition have found ways around their health problems, but they say more employer support is needed.]]>
Shi En Kim doi:10.1038/d41586-024-00819-w Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00819-w 2024-03-18 Nature 10.1038/d41586-024-00819-w https://www.nature.com/articles/d41586-024-00819-w
<![CDATA[Can lessons from infants solve the problems of data-greedy AI?]]> https://www.nature.com/articles/d41586-024-00713-5 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00713-5

Words and images experienced by an infant wearing sensors during their daily life have led to efficient machine learning, pointing to the power of multimodal training signals and to the potentially exploitable statistics of real-life experience.]]>
Linda B. Smith doi:10.1038/d41586-024-00713-5 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00713-5 2024-03-18 Nature 10.1038/d41586-024-00713-5 https://www.nature.com/articles/d41586-024-00713-5
<![CDATA[Connecting girls in Brazil to inspiring female scientists]]> https://www.nature.com/articles/d41586-024-00804-3 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00804-3

Physicist Carolina Brito leads an initiative to smash gender stereotypes in science.]]>
Julie Gould doi:10.1038/d41586-024-00804-3 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00804-3 2024-03-18 Nature 10.1038/d41586-024-00804-3 https://www.nature.com/articles/d41586-024-00804-3
<![CDATA[‘Bandit’ algorithms help chemists to discover generally applicable conditions for reactions]]> https://www.nature.com/articles/d41586-024-00446-5 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00446-5

In organic chemistry, finding conditions that enable a broad range of compounds to undergo a particular type of reaction is highly desirable. However, conventional methods for doing so consume a lot of time and reagents. A machine-learning method has been developed that overcomes these problems.]]>
doi:10.1038/d41586-024-00446-5 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00446-5 2024-03-18 Nature 10.1038/d41586-024-00446-5 https://www.nature.com/articles/d41586-024-00446-5
<![CDATA[How to stop 'passing the harasser': universities urged to join information-sharing scheme]]> https://www.nature.com/articles/d41586-024-00795-1 Nature, Published online: 18 March 2024; doi:10.1038/d41586-024-00795-1

The Misconduct Disclosure Scheme would make it harder for perpetrators to hide their past, advocacy group says.]]>
Sarah Wild doi:10.1038/d41586-024-00795-1 Nature, Published online: 2024-03-18; | doi:10.1038/d41586-024-00795-1 2024-03-18 Nature 10.1038/d41586-024-00795-1 https://www.nature.com/articles/d41586-024-00795-1
<![CDATA[Verbose robots, and why some people love Bach: Books in Brief]]> https://www.nature.com/articles/d41586-024-00813-2 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00813-2

Andrew Robinson reviews five of the best science picks.]]>
Andrew Robinson doi:10.1038/d41586-024-00813-2 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00813-2 2024-03-15 Nature 10.1038/d41586-024-00813-2 https://www.nature.com/articles/d41586-024-00813-2
<![CDATA[Bird-flu threat disrupts Antarctic penguin studies]]> https://www.nature.com/articles/d41586-024-00807-0 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00807-0

Projects have been cancelled in an effort to curb the virus’s spread.]]>
Carissa Wong doi:10.1038/d41586-024-00807-0 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00807-0 2024-03-15 Nature 10.1038/d41586-024-00807-0 https://www.nature.com/articles/d41586-024-00807-0
<![CDATA[China’s giant underground neutrino lab prepares to probe cosmic mysteries]]> https://www.nature.com/articles/d41586-024-00694-5 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00694-5

Due to come online this year, the JUNO facility will help to determine which type of neutrino has the highest mass — one of the biggest mysteries in physics.]]>
Gemma Conroy doi:10.1038/d41586-024-00694-5 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00694-5 2024-03-15 Nature 10.1038/d41586-024-00694-5 https://www.nature.com/articles/d41586-024-00694-5
<![CDATA[People, passion, publishable: an early-career researcher’s checklist for prioritizing projects]]> https://www.nature.com/articles/d41586-024-00812-3 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00812-3

Stuck between several lines of research? Here’s how we decide which ones to pursue, say Elizabeth Tenney, Jacqueline Chen and McKenzie Preston.]]>
Elizabeth TenneyJacqueline M. Chen McKenzie Preston doi:10.1038/d41586-024-00812-3 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00812-3 2024-03-15 Nature 10.1038/d41586-024-00812-3 https://www.nature.com/articles/d41586-024-00812-3
<![CDATA[Divas, captains, ghosts, ants and bumble-bees: collaborator attitudes explained]]> https://www.nature.com/articles/d41586-024-00808-z Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00808-z

Olga Lehmann made sense of challenges she faced in teamwork by analysing how she and her colleagues behaved and what she could have done differently.]]>
Olga Lehmann doi:10.1038/d41586-024-00808-z Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00808-z 2024-03-15 Nature 10.1038/d41586-024-00808-z https://www.nature.com/articles/d41586-024-00808-z
<![CDATA[A year in the life: what I learnt from using a time-tracking spreadsheet]]> https://www.nature.com/articles/d41586-024-00806-1 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00806-1

A low-tech solution helped Megan Rogers to increase her productivity and maintain a good work–life balance.]]>
Megan Rogers doi:10.1038/d41586-024-00806-1 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00806-1 2024-03-15 Nature 10.1038/d41586-024-00806-1 https://www.nature.com/articles/d41586-024-00806-1
<![CDATA[Why menopause keeps evolving in whales]]> https://www.nature.com/articles/d41586-024-00834-x Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00834-x

Long postreproductive lifespans might allow female whales to help their progeny survive. Plus, a sneak peek of China’s new underground neutrino lab and tips for PhD-holders looking for a job in industry.]]>
Flora Graham doi:10.1038/d41586-024-00834-x Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00834-x 2024-03-15 Nature 10.1038/d41586-024-00834-x https://www.nature.com/articles/d41586-024-00834-x
<![CDATA[First US drug approved for a liver disease surging around the world]]> https://www.nature.com/articles/d41586-024-00747-9 Nature, Published online: 15 March 2024; doi:10.1038/d41586-024-00747-9

A therapy called resmetirom improves hallmarks of an obesity-linked condition that can lead to liver failure.]]>
Heidi Ledford doi:10.1038/d41586-024-00747-9 Nature, Published online: 2024-03-15; | doi:10.1038/d41586-024-00747-9 2024-03-15 Nature 10.1038/d41586-024-00747-9 https://www.nature.com/articles/d41586-024-00747-9
<![CDATA[Publisher Correction: Durable CO<sub>2</sub> conversion in the proton-exchange membrane system]]> https://www.nature.com/articles/s41586-024-07289-0 Nature, Published online: 14 March 2024; doi:10.1038/s41586-024-07289-0

Publisher Correction: Durable CO2 conversion in the proton-exchange membrane system]]>
2 conversion in the proton-exchange membrane system]]> Wensheng FangWei GuoRuihu LuYa YanXiaokang LiuDan WuFu Min LiYansong ZhouChaohui HeChenfeng XiaHuiting NiuSicong WangYouwen LiuYu MaoChengyi ZhangBo YouYuanjie PangLele DuanXuan YangFei SongTianyou ZhaiGuoxiong WangXingpeng GuoBien TanTao YaoZiyun WangBao Yu Xia doi:10.1038/s41586-024-07289-0 Nature, Published online: 2024-03-14; | doi:10.1038/s41586-024-07289-0 2024-03-14 Nature 10.1038/s41586-024-07289-0 https://www.nature.com/articles/s41586-024-07289-0
<![CDATA[A fundamental constant in physics gets an update]]> https://www.nature.com/articles/d41586-024-00732-2 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00732-2

Scientists controlled a hydrogen atom with electric fields to derive a highly precise estimate of the Rydberg constant.]]>
doi:10.1038/d41586-024-00732-2 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00732-2 2024-03-14 Nature 10.1038/d41586-024-00732-2 https://www.nature.com/articles/d41586-024-00732-2
<![CDATA[Ditching ‘Anthropocene’: why ecologists say the term still matters]]> https://www.nature.com/articles/d41586-024-00786-2 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00786-2

Beyond stratigraphic definitions, the name has broader significance for understanding humans’ place on Earth.]]>
David Adam doi:10.1038/d41586-024-00786-2 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00786-2 2024-03-14 Nature 10.1038/d41586-024-00786-2 https://www.nature.com/articles/d41586-024-00786-2
<![CDATA[A Black mathematical history]]> https://www.nature.com/articles/d41586-024-00798-y Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00798-y

Documentary reveals how Black US scholars shaped today’s mathematics community and provides hope for the future.]]>
Noelle Sawyer doi:10.1038/d41586-024-00798-y Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00798-y 2024-03-14 Nature 10.1038/d41586-024-00798-y https://www.nature.com/articles/d41586-024-00798-y
<![CDATA[More than 4,000 plastic chemicals are hazardous, report finds]]> https://www.nature.com/articles/d41586-024-00805-2 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00805-2

Year-long effort compiles comprehensive database of chemicals in plastics.]]>
Nicola Jones doi:10.1038/d41586-024-00805-2 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00805-2 2024-03-14 Nature 10.1038/d41586-024-00805-2 https://www.nature.com/articles/d41586-024-00805-2
<![CDATA[The neuroscientist formerly known as Prince’s audio engineer]]> https://www.nature.com/articles/d41586-024-00791-5 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00791-5

Susan Rogers worked with the legendary singer-songwriter before earning a PhD in her 50s on auditory memory and how we listen to music throughout life.]]>
Anne Gulland doi:10.1038/d41586-024-00791-5 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00791-5 2024-03-14 Nature 10.1038/d41586-024-00791-5 https://www.nature.com/articles/d41586-024-00791-5
<![CDATA[Do black holes explode? The 50-year-old puzzle that challenges quantum physics]]> https://www.nature.com/articles/d41586-024-00768-4 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00768-4

Stephen Hawking’s paradoxical finding that black holes don’t live forever has profound, unresolved implications for the quest for unifying theories of reality.]]>
Davide Castelvecchi doi:10.1038/d41586-024-00768-4 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00768-4 2024-03-14 Nature 10.1038/d41586-024-00768-4 https://www.nature.com/articles/d41586-024-00768-4
<![CDATA[Fungal diseases are spreading undetected]]> https://www.nature.com/articles/d41586-024-00751-z Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00751-z

Low- and middle-income countries are grappling with widespread shortages of diagnostic tests for infections that kill millions.]]>
Charles Schmidt doi:10.1038/d41586-024-00751-z Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00751-z 2024-03-14 Nature 10.1038/d41586-024-00751-z https://www.nature.com/articles/d41586-024-00751-z
<![CDATA[Daily briefing: How Hawking’s paradox still puzzles physicists]]> https://www.nature.com/articles/d41586-024-00811-4 Nature, Published online: 14 March 2024; doi:10.1038/d41586-024-00811-4

On the sixth anniversary of Stephen Hawking’s death, we revisit his landmark paper. Plus, a stunning 3D atlas of the heart and the mysterious rise of cancer in young people.]]>
Flora Graham doi:10.1038/d41586-024-00811-4 Nature, Published online: 2024-03-14; | doi:10.1038/d41586-024-00811-4 2024-03-14 Nature 10.1038/d41586-024-00811-4 https://www.nature.com/articles/d41586-024-00811-4
<![CDATA[Publisher Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and T<sub>reg</sub> cells]]> https://www.nature.com/articles/s41586-024-07280-9 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07280-9

Publisher Correction: Anti-TIGIT antibody improves PD-L1 blockade through myeloid and Treg cells]]>
reg cells]]> Xiangnan GuanRuozhen HuYoonha ChoiShyam SrivatsBarzin Y. NabetJohn SilvaLisa McGinnisRobert HendricksKatherine NutschKarl L. BantaEllen DuongAlexis DunklePatrick S. ChangChia-Jung HanStephanie MittmanNandini MoldenPallavi DaggumatiWendy ConnollyMelissa JohnsonDelvys Rodriguez AbreuByoung Chul ChoAntoine ItalianoIgnacio Gil-BazoEnriqueta FelipIra MellmanSanjeev MariathasanDavid S. ShamesRaymond MengEugene Y. ChiangRobert J. JohnstonNamrata S. Patil doi:10.1038/s41586-024-07280-9 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07280-9 2024-03-13 Nature 10.1038/s41586-024-07280-9 https://www.nature.com/articles/s41586-024-07280-9
<![CDATA[Publisher Correction: Nuclear export of circular RNA]]> https://www.nature.com/articles/s41586-024-07281-8 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07281-8

Publisher Correction: Nuclear export of circular RNA]]>
Linh H. NgoAndrew G. BertB. Kate DredgeTobias WilliamsVincent MurphyWanqiu LiWilliam B. HamiltonKirstyn T. CareyJohn ToubiaKatherine A. PillmanDawei LiuJessica DesogusJeffrey A. ChaoAndrew J. DeansGregory J. GoodallVihandha O. Wickramasinghe doi:10.1038/s41586-024-07281-8 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07281-8 2024-03-13 Nature 10.1038/s41586-024-07281-8 https://www.nature.com/articles/s41586-024-07281-8
<![CDATA[Building a heart atlas: researchers map organ in stunning detail]]> https://www.nature.com/articles/d41586-024-00775-5 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00775-5

Cutting edge imaging techniques reveal how cells organise as the heart develops.]]>
Dan Fox doi:10.1038/d41586-024-00775-5 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00775-5 2024-03-13 Nature 10.1038/d41586-024-00775-5 https://www.nature.com/articles/d41586-024-00775-5
<![CDATA[Pooling babies’ saliva helps catch grave infection in newborns]]> https://www.nature.com/articles/d41586-024-00733-1 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00733-1

Cost-saving strategy increases early detection of congenital cytomegalovirus, which can cause developmental problems if left untreated.]]>
doi:10.1038/d41586-024-00733-1 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00733-1 2024-03-13 Nature 10.1038/d41586-024-00733-1 https://www.nature.com/articles/d41586-024-00733-1
<![CDATA[These cyborg jellyfish could monitor the changing seas]]> https://www.nature.com/articles/d41586-024-00731-3 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00731-3

A hat-like prosthesis helps the invertebrates to swim more efficiently and can be used to carry ocean sensors.]]>
doi:10.1038/d41586-024-00731-3 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00731-3 2024-03-13 Nature 10.1038/d41586-024-00731-3 https://www.nature.com/articles/d41586-024-00731-3
<![CDATA[Couple-close construction of polycyclic rings from diradicals]]> https://www.nature.com/articles/s41586-024-07181-x Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07181-x

A couple-close approach used to build semisaturated ring systems from dual radical precursors allows sampling of regions of underexplored chemical space, leading to an annulation that can be used for late-stage functionalization of pharmaceutical scaffolds.]]>
Alice LongChristian J. OswoodChristopher B. KellyMarian C. BryanDavid W. C. MacMillan doi:10.1038/s41586-024-07181-x Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07181-x 2024-03-13 Nature 10.1038/s41586-024-07181-x https://www.nature.com/articles/s41586-024-07181-x
<![CDATA[Neural and behavioural state switching during hippocampal dentate spikes]]> https://www.nature.com/articles/s41586-024-07192-8 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07192-8

The hippocampal dentate spike, an understudied population event that frequently occurs between sharp-wave ripples, may underlie a mechanism re-engaging the brain with the external world during synchronous population events, and support memory during non-locomotor behaviour.]]>
Jordan S. FarrellErnie HwaunBarna DudokIvan Soltesz doi:10.1038/s41586-024-07192-8 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07192-8 2024-03-13 Nature 10.1038/s41586-024-07192-8 https://www.nature.com/articles/s41586-024-07192-8
<![CDATA[US oil and gas system emissions from nearly one million aerial site measurements]]> https://www.nature.com/articles/s41586-024-07117-5 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07117-5

We integrate approximately one million aerial site measurements into regional emissions inventories for six regions in the USA, finding methane emission intensities that vary by more than a factor of ten.]]>
Evan D. SherwinJeffrey S. RutherfordZhan ZhangYuanlei ChenErin B. WetherleyPetr V. YakovlevElena S. F. BermanBrian B. JonesDaniel H. CusworthAndrew K. ThorpeAlana K. AyasseRiley M. DurenAdam R. Brandt doi:10.1038/s41586-024-07117-5 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07117-5 2024-03-13 Nature 10.1038/s41586-024-07117-5 https://www.nature.com/articles/s41586-024-07117-5
<![CDATA[AIRE relies on Z-DNA to flag gene targets for thymic T cell tolerization]]> https://www.nature.com/articles/s41586-024-07169-7 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07169-7

Z-DNA anchors the AIRE-mediated transcriptional program by enhancing the generation of double-stranded breaks and promoter poising.]]>
Yuan FangKushagra BansalSara MostafaviChristophe BenoistDiane Mathis doi:10.1038/s41586-024-07169-7 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07169-7 2024-03-13 Nature 10.1038/s41586-024-07169-7 https://www.nature.com/articles/s41586-024-07169-7
<![CDATA[Blueprinting extendable nanomaterials with standardized protein blocks]]> https://www.nature.com/articles/s41586-024-07188-4 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07188-4

A study describes an approach using designed building blocks that are far more regular in geometry than natural proteins to construct modular multicomponent protein assemblies.]]>
Timothy F. HuddyYang HsiaRyan D. KiblerJinwei XuNeville BethelDeepesh NagarajanRachel RedlerPhilip J. Y. LeungConnor WeidleAlexis CourbetErin C. YangAsim K. BeraNicolas CoudrayS. John CaliseFatima A. Davila-HernandezHannah L. HanKenneth D. CarrZhe LiRyan McHughGabriella ReggianoAlex KangBanumathi SankaranMiles S. DickinsonBrian CoventryT. J. BrunetteYulai LiuJustas DauparasAndrew J. BorstDamian EkiertJustin M. KollmanGira BhabhaDavid Baker doi:10.1038/s41586-024-07188-4 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07188-4 2024-03-13 Nature 10.1038/s41586-024-07188-4 https://www.nature.com/articles/s41586-024-07188-4
<![CDATA[Spatially organized cellular communities form the developing human heart]]> https://www.nature.com/articles/s41586-024-07171-z Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07171-z

Combining single-cell RNA-sequencing with high-resolution multiplexed error-robust fluorescence in situ hybridization reveals in detail the cellular interactions and specialization of cardiac cell types that form and remodel the human heart.]]>
Elie N. FarahRobert K. HuColin KernQingquan ZhangTing-Yu LuQixuan MaShaina TranBo ZhangDaniel CarlinAlexander MonellAndrew P. BlairZilu WangJacqueline EschbachBin LiEugin DesticiBing RenSylvia M. EvansShaochen ChenQuan ZhuNeil C. Chi doi:10.1038/s41586-024-07171-z Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07171-z 2024-03-13 Nature 10.1038/s41586-024-07171-z https://www.nature.com/articles/s41586-024-07171-z
<![CDATA[High-speed and large-scale intrinsically stretchable integrated circuits]]> https://www.nature.com/articles/s41586-024-07096-7 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07096-7

High-density, intrinsically stretchable transistors with high driving ability and integrated circuits with high operation speed and large-scale integration were enabled by a combination of innovations in materials, fabrication process design, device engineering and circuit design.]]>
Donglai ZhongCan WuYuanwen JiangYujia YuanMin-gu KimYuya NishioChien-Chung ShihWeichen WangJian-Cheng LaiXiaozhou JiTheodore Z. GaoYi-Xuan WangChengyi XuYu ZhengZhiao YuHuaxin GongNaoji MatsuhisaChuanzhen ZhaoYusheng LeiDeyu LiuSong ZhangYuto OchiaiShuhan LiuShiyuan WeiJeffrey B.-H. TokZhenan Bao doi:10.1038/s41586-024-07096-7 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07096-7 2024-03-13 Nature 10.1038/s41586-024-07096-7 https://www.nature.com/articles/s41586-024-07096-7
<![CDATA[Substrate-induced condensation activates plant TIR domain proteins]]> https://www.nature.com/articles/s41586-024-07183-9 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07183-9

Binding of the substrates NAD+ and ATP to the plant Toll/interleukin-1 receptor (TIR) domain proteins induces phase separation and, thereby, activation of TIR enzymatic and immune signalling activity.]]>
Wen SongLi LiuDongli YuHanna BernardyJan JirschitzkaShijia HuangAolin JiaWictoria JemielniakJulia AckerHenriette LaessleJunli WangQiaochu ShenWeijie ChenPilong LiJane E. ParkerZhifu HanPaul Schulze-LefertJijie Chai doi:10.1038/s41586-024-07183-9 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07183-9 2024-03-13 Nature 10.1038/s41586-024-07183-9 https://www.nature.com/articles/s41586-024-07183-9
<![CDATA[Drought triggers and sustains overnight fires in North America]]> https://www.nature.com/articles/s41586-024-07028-5 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07028-5

By examining the hourly diurnal cycle of 23,557 fires in North America during 2017–2020, 1,095 overnight burning events were identified, mostly associated with extreme fires and driven by long-term drought conditions.]]>
Kaiwei LuoXianli WangMark de JongMike Flannigan doi:10.1038/s41586-024-07028-5 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07028-5 2024-03-13 Nature 10.1038/s41586-024-07028-5 https://www.nature.com/articles/s41586-024-07028-5
<![CDATA[Dopamine receptor D2 confers colonization resistance via microbial metabolites]]> https://www.nature.com/articles/s41586-024-07179-5 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07179-5

In a mouse model of enteric pathogen infection, tryptophan metabolites protect against infection via activation of dopamine receptor D2 and regulation of actin cytoskeletal organization in intestinal epithelial cells.]]>
Samantha A. ScottJingjing FuPamela V. Chang doi:10.1038/s41586-024-07179-5 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07179-5 2024-03-13 Nature 10.1038/s41586-024-07179-5 https://www.nature.com/articles/s41586-024-07179-5
<![CDATA[Time-resolved cryo-EM of G-protein activation by a GPCR]]> https://www.nature.com/articles/s41586-024-07153-1 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07153-1

Time-resolved cryo-EM is used to capture structural transitions during G-protein activation stimulated by a G-protein-coupled receptor.]]>
Makaía M. Papasergi-ScottGuillermo Pérez-HernándezHossein BatebiYang GaoGözde EskiciAlpay B. SevenOuliana PanovaDaniel HilgerMarina CasiraghiFeng HeLuis MaulPeter GmeinerBrian K. KobilkaPeter W. HildebrandGeorgios Skiniotis doi:10.1038/s41586-024-07153-1 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07153-1 2024-03-13 Nature 10.1038/s41586-024-07153-1 https://www.nature.com/articles/s41586-024-07153-1
<![CDATA[Mitochondrial complex I activity in microglia sustains neuroinflammation]]> https://www.nature.com/articles/s41586-024-07167-9 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07167-9

Blocking mitochondrial complex I in pro-inflammatory microglia protects the central nervous system against neurotoxic damage and improves functional outcomes in vivo in an animal disease model.]]>
L. Peruzzotti-JamettiC. M. WillisG. KrzakR. HamelL. PirvanR.-B. IonescuJ. A. ReiszH. A. PragM. E. Garcia-SeguraV. WuY. XiangB. BarlasA. M. CaseyA. M. R. van den BoschA. M. NicaiseL. RothG. R. BatesH. HuangP. PrasadA. E. VincentC. FrezzaC. ViscomiG. BalmusZ. TakatsJ. C. MarioniA. D’AlessandroM. P. MurphyI. MohorianuS. Pluchino doi:10.1038/s41586-024-07167-9 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07167-9 2024-03-13 Nature 10.1038/s41586-024-07167-9 https://www.nature.com/articles/s41586-024-07167-9
<![CDATA[Last-mile delivery increases vaccine uptake in Sierra Leone]]> https://www.nature.com/articles/s41586-024-07158-w Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07158-w

A cluster randomized controlled trial in Sierra Leone shows that targeting access to vaccines in remote areas increases uptake, an approach that can be used to improve vaccine equity in developing countries.]]>
Niccolò F. MeriggiMaarten VoorsMadison LevineVasudha RamakrishnaDesmond Maada KangbaiMichael RozelleElla TylerSellu KallonJunisa NabieuSarah CundyAhmed Mushfiq Mobarak doi:10.1038/s41586-024-07158-w Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07158-w 2024-03-13 Nature 10.1038/s41586-024-07158-w https://www.nature.com/articles/s41586-024-07158-w
<![CDATA[Roll-to-roll, high-resolution 3D printing of shape-specific particles]]> https://www.nature.com/articles/s41586-024-07061-4 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07061-4

We introduce a scalable, high-resolution, 3D printing technique for the fabrication of shape-specific particles based on roll-to-roll continuous liquid interface production, enabling direct integration within biomedical, analytical and advanced materials applications.]]>
Jason M. KronenfeldLukas RotherMax A. SacconeMaria T. DulayJoseph M. DeSimone doi:10.1038/s41586-024-07061-4 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07061-4 2024-03-13 Nature 10.1038/s41586-024-07061-4 https://www.nature.com/articles/s41586-024-07061-4
<![CDATA[Rapid unleashing of macrophage efferocytic capacity via transcriptional pause release]]> https://www.nature.com/articles/s41586-024-07172-y Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07172-y

Macrophages are revealed to adopt a polymerase II pause/release process to effectively deal with ingested apoptotic corpses and for continuous efferocytosis.]]>
Turan TufanGamze ComertpayAmbra VillaniGeoffrey M. NelsonMarina TerekhovaShannon KelleyPavel ZakharovRochelle M. EllisonOleg ShpynovMichael RaymondJerry SunYitan ChenEnno BockelmannMarta StremskaLance W. PetersonLaura BoeckaertsSeth R. GoldmanJ. Iker EtchegarayMaxim N. ArtyomovFrancesca PeriKodi S. Ravichandran doi:10.1038/s41586-024-07172-y Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07172-y 2024-03-13 Nature 10.1038/s41586-024-07172-y https://www.nature.com/articles/s41586-024-07172-y
<![CDATA[Evolutionary trajectories of small cell lung cancer under therapy]]> https://www.nature.com/articles/s41586-024-07177-7 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07177-7

We uncover key processes of the genomic evolution of small cell lung cancer under therapy, identify the common ancestor as the source of clonal diversity at relapse and show central genomic patterns associated with drug response.]]>
Julie GeorgeLukas MaasNima AbedpourMaria CartolanoLaura KaiserRieke N. FischerAndreas H. ScheelJan-Philipp WeberMartin HellmichGraziella BoscoCaroline VolzChristian MuellerIlona DahmenFelix JohnCleidson Padua AlvesLisa WerrJens Peter PanseMartin KirschnerWalburga Engel-RiedelJessica JürgensErich StoelbenMichael BrockmannStefan GrauMartin SebastianJan A. StratmannJens KernHorst-Dieter HummelBalazs HegedüsMartin SchulerTill PlönesClemens AignerThomas ElterKarin ToepeltYon-Dschun KoSylke KurzChristian GrohéMonika SerkeKatja HöpkerLars HagmeyerFabian DoerrKhosro HekmathJudith StrapatsasKarl-Otto KambartelGeothy ChakupurakalAnnette BuschFranz-Georg BauernfeindFrank GriesingerAnne LuersWiebke DirksRainer WiewrodtAndrea LueckeErnst RodermannAndreas DielVolker HagenKai SeverinRoland T. UllrichHans Christian ReinhardtAlexander QuaasMagdalena BogusCornelius CourtsPeter NürnbergKerstin BeckerViktor AchterReinhard BüttnerJürgen WolfMartin PeiferRoman K. Thomas doi:10.1038/s41586-024-07177-7 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07177-7 2024-03-13 Nature 10.1038/s41586-024-07177-7 https://www.nature.com/articles/s41586-024-07177-7
<![CDATA[Penning micro-trap for quantum computing]]> https://www.nature.com/articles/s41586-024-07111-x Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07111-x

A micro-fabricated Penning trap that operates at a 3 T magnetic field demonstrates full quantum control of an ion and the ability to transport the ion arbitrarily in the trapping plane above the chip.]]>
Shreyans JainTobias SägesserPavel HrmoCeleste TorkzabanMartin StadlerRobin OswaldChris AxlineAmado Bautista-SalvadorChristian OspelkausDaniel KienzlerJonathan Home doi:10.1038/s41586-024-07111-x Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07111-x 2024-03-13 Nature 10.1038/s41586-024-07111-x https://www.nature.com/articles/s41586-024-07111-x
<![CDATA[Global supply chains amplify economic costs of future extreme heat risk]]> https://www.nature.com/articles/s41586-024-07147-z Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07147-z

A global high-resolution disaster footprint analytical model is developed to show substantial socioeconomic impacts from climatic change-driven heat stress through the global supply chain by 2060 due to direct and indirect effects on health and labour productivity.]]>
Yida SunShupeng ZhuDaoping WangJianping DuanHui LuHao YinChang TanLingrui ZhangMengzhen ZhaoWenjia CaiYong WangYixin HuShu TaoDabo Guan doi:10.1038/s41586-024-07147-z Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07147-z 2024-03-13 Nature 10.1038/s41586-024-07147-z https://www.nature.com/articles/s41586-024-07147-z
<![CDATA[The evolution of menopause in toothed whales]]> https://www.nature.com/articles/s41586-024-07159-9 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07159-9

A comparative analysis tests competing evolutionary hypotheses in toothed whales in which menopause has evolved many times as females extended their overall lifespan but not their reproductive lifespan, increasing their opportunity for intergenerational help without increasing intergenerational reproductive competition.]]>
Samuel EllisDaniel W. FranksMia Lybkær Kronborg NielsenMichael N. WeissDarren P. Croft doi:10.1038/s41586-024-07159-9 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07159-9 2024-03-13 Nature 10.1038/s41586-024-07159-9 https://www.nature.com/articles/s41586-024-07159-9
<![CDATA[Neural signatures of natural behaviour in socializing macaques]]> https://www.nature.com/articles/s41586-024-07178-6 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07178-6

Single-neuron and population activity in the macaque prefrontal and temporal cortex robustly encodes 24 species-typical behaviours, reciprocity in social interactions and social support.]]>
Camille TestardSébastien TremblayFelipe ParodiRon W. DiTullioArianna Acevedo-IthierKristin L. GardinerKonrad KordingMichael L. Platt doi:10.1038/s41586-024-07178-6 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07178-6 2024-03-13 Nature 10.1038/s41586-024-07178-6 https://www.nature.com/articles/s41586-024-07178-6
<![CDATA[Self-enhanced mobility enables vortex pattern formation in living matter]]> https://www.nature.com/articles/s41586-024-07114-8 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07114-8

We demonstrate that self-enhanced mobility offers a simple physical mechanism for pattern formation in living systems and, more generally, in other active matter systems near the boundary of fluid- and solid-like behaviours.]]>
Haoran XuYilin Wu doi:10.1038/s41586-024-07114-8 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07114-8 2024-03-13 Nature 10.1038/s41586-024-07114-8 https://www.nature.com/articles/s41586-024-07114-8
<![CDATA[Anoxygenic phototroph of the Chloroflexota uses a type I reaction centre]]> https://www.nature.com/articles/s41586-024-07180-y Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07180-y

Cultivation of a new anoxygenic phototrophic bacterium from Boreal Shield lake water—representing a transition form in the evolution of photosynthesis—offers insights into how the major modes of phototrophy diversified.]]>
J. M. TsujiN. A. ShawS. NagashimaJ. J. VenkiteswaranS. L. SchiffT. WatanabeM. FukuiS. HanadaM. TankJ. D. Neufeld doi:10.1038/s41586-024-07180-y Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07180-y 2024-03-13 Nature 10.1038/s41586-024-07180-y https://www.nature.com/articles/s41586-024-07180-y
<![CDATA[APOE4/4 is linked to damaging lipid droplets in Alzheimer’s disease microglia]]> https://www.nature.com/articles/s41586-024-07185-7 Nature, Published online: 13 March 2024; doi:10.1038/s41586-024-07185-7

A microglial state, featuring lipid droplets and secretion of neurotoxic factors, is shown to be most prominent in people with Alzheimer’s disease who have the APOE4 genotype.]]>
Michael S. HaneyRóbert PálovicsChristy Nicole MunsonChris LongPatrik K. JohanssonOscar YipWentao DongEshaan RawatElizabeth WestJohannes C. M. SchlachetzkiAndy TsaiIan Hunter GuldnerBhawika S. LamichhaneAmanda SmithNicholas SchaumKruti CalcuttawalaAndrew ShinYung-Hua WangChengzhong WangNicole KoutsodendrisGeidy E. SerranoThomas G. BeachEric M. ReimanChristopher K. GlassMonther Abu-RemailehAnnika EnejderYadong HuangTony Wyss-Coray doi:10.1038/s41586-024-07185-7 Nature, Published online: 2024-03-13; | doi:10.1038/s41586-024-07185-7 2024-03-13 Nature 10.1038/s41586-024-07185-7 https://www.nature.com/articles/s41586-024-07185-7
<![CDATA[Chatbot AI makes racist judgements on the basis of dialect]]> https://www.nature.com/articles/d41586-024-00779-1 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00779-1

Some large language models harbour hidden biases that cannot be removed using standard methods.]]>
Elizabeth Gibney doi:10.1038/d41586-024-00779-1 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00779-1 2024-03-13 Nature 10.1038/d41586-024-00779-1 https://www.nature.com/articles/d41586-024-00779-1
<![CDATA[Drought-fuelled overnight burning propels large fires in North America]]> https://www.nature.com/articles/d41586-024-00536-4 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00536-4

Burning events that occur at night have been revealed as a driver of large wildfires. Prolonged drought conditions are to blame, making it easier for fires to spread at night when they would ordinarily slow or extinguish completely.]]>
Jennifer K. BalchAdam L. Mahood doi:10.1038/d41586-024-00536-4 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00536-4 2024-03-13 Nature 10.1038/d41586-024-00536-4 https://www.nature.com/articles/d41586-024-00536-4
<![CDATA[Plutopalooza]]> https://www.nature.com/articles/d41586-024-00748-8 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00748-8

It’s the end of the world as we know it.]]>
Gretchen Tessmer doi:10.1038/d41586-024-00748-8 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00748-8 2024-03-13 Nature 10.1038/d41586-024-00748-8 https://www.nature.com/articles/d41586-024-00748-8
<![CDATA[Mobile delivery of COVID-19 vaccines improved uptake in rural Sierra Leone]]> https://www.nature.com/articles/d41586-023-03186-0 Nature, Published online: 13 March 2024; doi:10.1038/d41586-023-03186-0

A trial that took mobile health services to rural Sierra Leone finds that this initiative increased COVID-19 vaccine uptake. But more must be done to expand the coverage of health services in low-income countries.]]>
Alison ButtenheimHarsha Thirumurthy doi:10.1038/d41586-023-03186-0 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-023-03186-0 2024-03-13 Nature 10.1038/d41586-023-03186-0 https://www.nature.com/articles/d41586-023-03186-0
<![CDATA[Numbers highlight US dominance in clinical research]]> https://www.nature.com/articles/d41586-024-00755-9 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00755-9

Institutions from the country make unrivaled contributions to high-quality health-sciences research in the Nature Index.]]>
doi:10.1038/d41586-024-00755-9 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00755-9 2024-03-13 Nature 10.1038/d41586-024-00755-9 https://www.nature.com/articles/d41586-024-00755-9
<![CDATA[Did ‘alien’ debris hit Earth? Startling claim sparks row at scientific meeting]]> https://www.nature.com/articles/d41586-024-00774-6 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00774-6

Astrophysicist Avi Loeb says that an interstellar meteor showered Earth with particles. At a planetary-science conference this week, researchers begged to differ.]]>
Alexandra Witze doi:10.1038/d41586-024-00774-6 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00774-6 2024-03-13 Nature 10.1038/d41586-024-00774-6 https://www.nature.com/articles/d41586-024-00774-6
<![CDATA[Three actions PhD-holders should take to land their next job]]> https://www.nature.com/articles/d41586-024-00727-z Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00727-z

A hiring manager reveals the lessons he learnt when transitioning from a PhD programme to industry.]]>
Fawzi Abou-Chahine doi:10.1038/d41586-024-00727-z Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00727-z 2024-03-13 Nature 10.1038/d41586-024-00727-z https://www.nature.com/articles/d41586-024-00727-z
<![CDATA[How AI is being used to accelerate clinical trials]]> https://www.nature.com/articles/d41586-024-00753-x Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00753-x

From study design to patient recruitment, researchers are investigating ways that technology could speed up the process.]]>
Matthew Hutson doi:10.1038/d41586-024-00753-x Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00753-x 2024-03-13 Nature 10.1038/d41586-024-00753-x https://www.nature.com/articles/d41586-024-00753-x
<![CDATA[A guide to the Nature Index]]> https://www.nature.com/articles/d41586-024-00758-6 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00758-6

A description of the terminology and methodology used in this supplement, and a guide to the functionality that is available free online at natureindex.com.]]>
doi:10.1038/d41586-024-00758-6 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00758-6 2024-03-13 Nature 10.1038/d41586-024-00758-6 https://www.nature.com/articles/d41586-024-00758-6
<![CDATA[Peer-replication model aims to address science’s ‘reproducibility crisis’]]> https://www.nature.com/articles/d41586-024-00796-0 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00796-0

Researchers propose that independent attempts to replicate results should complement conventional peer review.]]>
James Mitchell Crow doi:10.1038/d41586-024-00796-0 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00796-0 2024-03-13 Nature 10.1038/d41586-024-00796-0 https://www.nature.com/articles/d41586-024-00796-0
<![CDATA[Daily briefing: In most mammal species, males and females are the same size — or females are bigger]]> https://www.nature.com/articles/d41586-024-00800-7 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00800-7

Charles Darwin’s claim about male mammals usually being bigger than females is proved wrong. Plus, OpenAI’s Sora can create amazing video from text prompts, and what’s wrong with how we treat the menopause.]]>
Flora Graham doi:10.1038/d41586-024-00800-7 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00800-7 2024-03-13 Nature 10.1038/d41586-024-00800-7 https://www.nature.com/articles/d41586-024-00800-7
<![CDATA[Why are so many young people getting cancer? What the data say]]> https://www.nature.com/articles/d41586-024-00720-6 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00720-6

Clues to a modern mystery could be lurking in information collected generations ago.]]>
Heidi Ledford doi:10.1038/d41586-024-00720-6 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00720-6 2024-03-13 Nature 10.1038/d41586-024-00720-6 https://www.nature.com/articles/d41586-024-00720-6
<![CDATA[Ancient malaria genome from Roman skeleton hints at disease’s history]]> https://www.nature.com/articles/d41586-024-00772-8 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00772-8

Genetic information from ancient remains is helping to reveal how malaria has moved and evolved alongside people.]]>
Tosin Thompson doi:10.1038/d41586-024-00772-8 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00772-8 2024-03-13 Nature 10.1038/d41586-024-00772-8 https://www.nature.com/articles/d41586-024-00772-8
<![CDATA[Deadly brain cancer shrinks after CAR-T therapy — but for how long is unclear]]> https://www.nature.com/articles/d41586-024-00704-6 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00704-6

Early studies with engineered immune cells show drastic but often short-lived results in glioblastoma, the most aggressive brain cancer.]]>
Heidi Ledford doi:10.1038/d41586-024-00704-6 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00704-6 2024-03-13 Nature 10.1038/d41586-024-00704-6 https://www.nature.com/articles/d41586-024-00704-6
<![CDATA[Researchers call for a major rethink of how Alzheimer’s treatments are evaluated]]> https://www.nature.com/articles/d41586-024-00756-8 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00756-8

An approach that aims to quantify how long a drug can delay or halt the progression of disease is gathering steam.]]>
Esther Landhuis doi:10.1038/d41586-024-00756-8 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00756-8 2024-03-13 Nature 10.1038/d41586-024-00756-8 https://www.nature.com/articles/d41586-024-00756-8
<![CDATA[3D printing enables mass production of microcomponents]]> https://www.nature.com/articles/d41586-024-00492-z Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00492-z

Combining a high-throughput technique with 3D printing offers a way of fabricating micrometre-sized particles for use in electronics and biotechnology. The versatile method can produce one million intricate shapes in a single day.]]>
Christoph A. SpiegelEva Blasco doi:10.1038/d41586-024-00492-z Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00492-z 2024-03-13 Nature 10.1038/d41586-024-00492-z https://www.nature.com/articles/d41586-024-00492-z
<![CDATA[Killer whales have menopause. Now scientists think they know why]]> https://www.nature.com/articles/d41586-024-00794-2 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00794-2

Data suggest menopause evolved to enable older female whales to help younger generations survive, and how researchers made a cellular map of the developing human heart.]]>
Benjamin ThompsonNick Petrić Howe doi:10.1038/d41586-024-00794-2 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00794-2 2024-03-13 Nature 10.1038/d41586-024-00794-2 https://www.nature.com/articles/d41586-024-00794-2
<![CDATA[Massive public-health experiment sends vaccination rates soaring]]> https://www.nature.com/articles/d41586-024-00730-4 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00730-4

The rate of vaccination against COVID-19 rose sharply in villages in Sierra Leone where health officials held mobile vaccination clinics.]]>
Max Kozlov doi:10.1038/d41586-024-00730-4 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00730-4 2024-03-13 Nature 10.1038/d41586-024-00730-4 https://www.nature.com/articles/d41586-024-00730-4
<![CDATA[Anthony Epstein (1921–2024), discoverer of virus causing cancer in humans]]> https://www.nature.com/articles/d41586-024-00763-9 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00763-9

Pathologist whose finding that viruses can trigger tumours in humans transformed medical research.]]>
Alan Rickinson doi:10.1038/d41586-024-00763-9 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00763-9 2024-03-13 Nature 10.1038/d41586-024-00763-9 https://www.nature.com/articles/d41586-024-00763-9
<![CDATA[Four change-makers seek impact in medical research]]> https://www.nature.com/articles/d41586-024-00754-w Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00754-w

Bringing fresh perspectives to long-standing health challenges, these scientists are using techniques such as big-data analytics and AI to push the field.]]>
Amy CoombsSandy Ong doi:10.1038/d41586-024-00754-w Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00754-w 2024-03-13 Nature 10.1038/d41586-024-00754-w https://www.nature.com/articles/d41586-024-00754-w
<![CDATA[Epstein–Barr virus at 60]]> https://www.nature.com/articles/d41586-024-00653-0 Nature, Published online: 13 March 2024; doi:10.1038/d41586-024-00653-0

The 1964 discovery of Epstein–Barr virus shed light on factors that contribute to human cancer. Subsequent studies set the stage for finding ways to diagnose and treat cancer, and revealed how immune defences control viral infection.]]>
Lawrence S. Young doi:10.1038/d41586-024-00653-0 Nature, Published online: 2024-03-13; | doi:10.1038/d41586-024-00653-0 2024-03-13 Nature 10.1038/d41586-024-00653-0 https://www.nature.com/articles/d41586-024-00653-0