Review, News & Views, Perspectives, Hypotheses and Analyses

  • News & Views |

    Migration of brine shrimp causes substantial mixing of the water column.

    • Henry Gee
  • News & Views |

    The growth of gold nanoparticles has been manipulated using amino acids and peptides to produce twisted structures that alter the rotation of light. The method could simplify the development of optical devices.

    • Guillermo González-Rubio
    •  & Luis M. Liz-Marzán
  • News & Views |

    Inappropriate cellular inflammation can cause disease. It emerges that the protein SAMHD1 prevents the release of newly replicated DNA from the nucleus, blocking an undesirable pro-inflammatory response.

    • Madzia P. Crossley
    •  & Karlene A. Cimprich
  • News & Views |

    A method for integrating photonic devices with state-of-the-art nanoelectronics overcomes previous limitations. The approach shows promise for realizing high-speed, low-power optoelectronic technology.

    • Goran Z. Mashanovich
  • News & Views |

    Cancers of epithelial-cell origin often contain some tumour cells that have acquired traits of mesenchymal cells. How this leads to cancer spread has now been illuminated in mouse models.

    • Erik W. Thompson
    •  & Shivashankar H. Nagaraj
  • News & Views |

    People waiting for a liver transplant can die before an organ is found, or, if one is available but of poor quality, there is a risk of transplant failure. A machine that preserves livers might offer a way forward.

    • Stefan Schneeberger
  • News & Views |

    The full list of weapons used by bacteria against viruses is not known. A computational approach has uncovered nine previously unidentified antiviral systems, encoded by genes near known defence genes in bacterial genomes.

    • Sébastien Levesque
    •  & Sylvain Moineau
  • News & Views |

    X-ray observations have revealed a dozen stellar-mass black holes at the centre of the Galaxy, implying that there are thousands more to be found. The discovery confirms a fundamental prediction of stellar dynamics.

    • Mark R. Morris
  • News & Views |

    An epidemiological study of adolescents who had acquired HIV around the time of birth highlights how high-income countries benefit from the ability to begin treating all infected children in the first years of life.

    • Patricia M. Flynn
  • News & Views |

    The brain’s resident immune cells retain a long-lasting memory of peripheral inflammation. This memory can influence the response to stroke and the progression of Alzheimer’s disease in mouse models.

    • Alexi Nott
    •  & Christopher K. Glass
  • News & Views |

    Communication systems rely on random-number generators for the encryption of information. A method for producing truly random numbers even from untrustworthy devices could lead to improvements in security.

    • Stefano Pironio
  • News & Views |

    Single-cell analyses in cancer are limited by the small biomass of individual cells. In vitro production of 3D organoid structures from single tumour-derived cells generates sufficient biomass for in-depth analyses.

    • Calvin J. Kuo
    •  & Christina Curtis
  • News & Views |

    There are striking differences between the male and female forms of some species. A study of marine fossils finds that such differences come at the cost of an increased risk of extinction.

    • Hanna Kokko
  • News & Views |

    Evidence suggests that the circulation system of the North Atlantic Ocean is in a weakened state that is unprecedented in the past 1,600 years, but questions remain as to when exactly the decline commenced.

    • Summer K. Praetorius
  • News & Views |

    Researchers have demonstrated that atomically thin materials can be highly reflective, contrary to general thinking. This finding could have technological implications for nanophotonics, optoelectronics and quantum optics.

    • Kin Fai Mak
    •  & Jie Shan
  • News & Views |

    The evolutionary history of viruses is largely unknown. Large-scale discovery of vertebrate RNA viruses shows that, although viruses often jump between hosts, most have co-evolved with their hosts over millions of years.

    • Mark Zeller
    •  & Kristian G. Andersen
  • News & Views |

    Different forms of molecular crystals often have distinct properties, which can greatly influence their potential applications. A way of controlling the crystal form of a protein has now been reported.

    • Robert G. Alberstein
    •  & F. Akif Tezcan
  • News & Views |

    It is thought that plants sense water availability in the soil as a way of anticipating drought. The identification of a peptide expressed when water is scarce offers a chance to unravel the underlying molecular mechanism.

    • Alexander Christmann
    •  & Erwin Grill
  • News & Views |

    Cell-tracing analysis reveals that a disperse group of cells in the mouse liver express the enzyme telomerase, which preserves chromosome ends. These cells contribute to liver maintenance and regeneration.

    • Kenneth S. Zaret
  • News & Views |

    The Mississippi River is shackled by one of the world’s largest systems of flood control. A palaeohydrological record suggests that those measures might actually be making floods worse.

    • Scott St. George
  • News & Views |

    Chronic infections can be hard to treat because slow-growing bacteria known as persister cells are usually unharmed by antibiotics. The identification of molecules that target such cells might provide a solution.

    • Julian G. Hurdle
    •  & Aditi Deshpande
  • News & Views |

    The geometry of putative ancient shorelines on Mars suggests that these features were deformed by the growth of a massive volcanic region — a finding that has implications for the climate, geology and hydrology of early Mars.

    • Maria T. Zuber
  • News & Views |

    Software that devises effective schemes for synthetic chemistry has depended on the input of rules from researchers. A system is now reported in which an artificial-intelligence program learns the rules for itself.

    • Derek Lowe